Search Results
Overview
| Uniprot ID | P19086 |
|---|---|
| Protein Name | Guanine nucleotide-binding protein G(z) subunit alpha |
| Gene Name | GNAZ |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 51 | SGKSTIVKQMKIIHS |
Function
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems
Protein Sequence
10
MGCRQSSEEK
20
EAARRSRRID
30
RHLRSESQRQ
40
RREIKLLLLG
50
TSNSGKSTIV
60
KQMKIIHSGG
70
FNLEACKEYK
80
PLIIYNAIDS
90
LTRIIRALAA
100
LRIDFHNPDR
110
AYDAVQLFAL
120
TGPAESKGEI
130
TPELLGVMRR
140
LWADPGAQAC
150
FSRSSEYHLE
160
DNAAYYLNDL
170
ERIAAADYIP
180
TVEDILRSRD
190
MTTGIVENKF
200
TFKELTFKMV
210
DVGGQRSERK
220
KWIHCFEGVT
230
AIIFCVELSG
240
YDLKLYEDNQ
250
TSRMAESLRL
260
FDSICNNNWF
270
INTSLILFLN
280
KKDLLAEKIR
290
RIPLTICFPE
300
YKGQNTYEEA
310
AVYIQRQFED
320
LNRNKETKEI
330
YSHFTCATDT
340
SNIQFVFDAV
350
TDVIIQNNLK
YIGLC
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0044297 | cell body |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005834 | heterotrimeric G-protein complex |
| Cellular Component | GO:0005635 | nuclear envelope |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0010855 | adenylate cyclase inhibitor activity |
| Molecular Function | GO:0001664 | G protein-coupled receptor binding |
| Molecular Function | GO:0031821 | G protein-coupled serotonin receptor binding |
| Molecular Function | GO:0031683 | G-protein beta/gamma-subunit complex binding |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0003924 | GTPase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0007193 | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
| Biological Process | GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway |
| Biological Process | GO:0007186 | G protein-coupled receptor signaling pathway |
| Biological Process | GO:0046676 | negative regulation of insulin secretion |
Reference
[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.