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Overview

Uniprot IDP19945
Protein NameLarge ribosomal subunit protein uL10
Gene NameRplp0
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
10 REDRATWKSNYFLKI
106 RDMLLANKVPAAARA
50 IRMSLRGKAVVLMGK

Function

Ribosomal protein P0 is the functional equivalent of E.coli protein L10

Protein Sequence

10 MPREDRATWK 20 SNYFLKIIQL 30 LDDYPKCFIV 40 GADNVGSKQM 50 QQIRMSLRGK 60 AVVLMGKNTM 70 MRKAIRGHLE 80 NNPALEKLLP 90 HIRGNVGFVF 100 TKEDLTEIRD 110 MLLANKVPAA 120 ARAGAIAPCE 130 VTVPAQNTGL 140 GPEKTSFFQA 150 LGITTKISRG 160 TIEILSDVQL 170 IKTGDKVGAS 180 EATLLNMLNI 190 SPFSFGLIIQ 200 QVFDNGSIYS 210 PEVLDITEQA 220 LHTRFLEGVR 230 NVASVCLQIG 240 YPTVASVPHS 250 IINGYKRVLA 260 LSVETDYTFP 270 LAEKVKAFLA 280 DPSAFAAAAP 290 VAAATTAAPA 300 AAAAPAKVEA 310 KEESEESDED MGFGLFD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0036464 cytoplasmic ribonucleoprotein granule
Cellular Component GO:0005829 cytosol
Cellular Component GO:0022625 cytosolic large ribosomal subunit
Cellular Component GO:0022626 cytosolic ribosome
Cellular Component GO:0030425 dendrite
Cellular Component GO:0005634 nucleus
Cellular Component GO:0098794 postsynapse
Cellular Component GO:0014069 postsynaptic density
Cellular Component GO:0098793 presynapse
Cellular Component GO:1990904 ribonucleoprotein complex
Cellular Component GO:0005840 ribosome
Cellular Component GO:0045202 synapse
Molecular Function GO:0070180 large ribosomal subunit rRNA binding
Molecular Function GO:0042277 peptide binding
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0071320 cellular response to cAMP
Biological Process GO:0071353 cellular response to interleukin-4
Biological Process GO:1904628 cellular response to phorbol 13-acetate 12-myristate
Biological Process GO:1904401 cellular response to Thyroid stimulating hormone
Biological Process GO:0002181 cytoplasmic translation
Biological Process GO:0007595 lactation
Biological Process GO:0010269 response to selenium ion
Biological Process GO:0042254 ribosome biogenesis
Biological Process GO:0140242 translation at postsynapse
Biological Process GO:0140236 translation at presynapse

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.