Search Results
Overview
| Uniprot ID | P20774 |
|---|---|
| Protein Name | Mimecan |
| Gene Name | OGN |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 137 | KIKKLTAKDFADIPN |
| 188 | KLPVLPPKLTLFNAK |
| 195 | KLTLFNAKYNKIKSR |
| 198 | LFNAKYNKIKSRGIK |
| 205 | KIKSRGIKANAFKKL |
| 211 | IKANAFKKLNNLTFL |
| 281 | GNPIVLGKHPNSFIC |
| 290 | PNSFICLKRLPIGSY |
Function
Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2
Protein Sequence
10
MKTLQSTLLL
20
LLLVPLIKPA
30
PPTQQDSRII
40
YDYGTDNFEE
50
SIFSQDYEDK
60
YLDGKNIKEK
70
ETVIIPNEKS
80
LQLQKDEAIT
90
PLPPKKENDE
100
MPTCLLCVCL
110
SGSVYCEEVD
120
IDAVPPLPKE
130
SAYLYARFNK
140
IKKLTAKDFA
150
DIPNLRRLDF
160
TGNLIEDIED
170
GTFSKLSLLE
180
ELSLAENQLL
190
KLPVLPPKLT
200
LFNAKYNKIK
210
SRGIKANAFK
220
KLNNLTFLYL
230
DHNALESVPL
240
NLPESLRVIH
250
LQFNNIASIT
260
DDTFCKANDT
270
SYIRDRIEEI
280
RLEGNPIVLG
290
KHPNSFICLK
RLPIGSYF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0031012 | extracellular matrix |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:1903561 | extracellular vesicle |
| Cellular Component | GO:0140150 | gel phase of interstitial matrix |
| Cellular Component | GO:0005796 | Golgi lumen |
| Cellular Component | GO:0043202 | lysosomal lumen |
| Molecular Function | GO:0008083 | growth factor activity |
| Biological Process | GO:0061975 | articular cartilage development |
| Biological Process | GO:0060348 | bone development |
| Biological Process | GO:0048662 | negative regulation of smooth muscle cell proliferation |
Reference
[1] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.
[2] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.