Search Results
Overview
| Uniprot ID | P21531 |
|---|---|
| Protein Name | Large ribosomal subunit protein uL3 |
| Gene Name | Rpl3 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 103 | PRGLRTFKTVFAEHI |
| 115 | EHISDECKRRFYKNW |
| 120 | ECKRRFYKNWHKSKK |
| 132 | SKKKAFTKYCKKWQD |
| 136 | AFTKYCKKWQDDTGK |
| 155 | KDFNSMKKYCQVIRI |
| 229 | VTKGKGYKGVTSRWH |
| 250 | KTHRGLRKVACIGAW |
| 286 | EINKKIYKIGQGYLI |
| 294 | IGQGYLIKDGKLIKN |
| 300 | IKDGKLIKNNASTDY |
| 349 | KRVLTLRKSLLVQTK |
| 356 | KSLLVQTKRRALEKI |
| 366 | ALEKIDLKFIDTTSK |
| 373 | KFIDTTSKFGHGRFQ |
| 385 | RFQTMEEKKAFMGPL |
| 386 | FQTMEEKKAFMGPLK |
| 393 | KAFMGPLKKDRIAKE |
| 66 | EVDRPGSKVNKKEVV |
Function
Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell
Protein Sequence
10
MSHRKFSAPR
20
HGSLGFLPRK
30
RSSRHRGKVK
40
SFPKDDPSKP
50
VHLTAFLGYK
60
AGMTHIVREV
70
DRPGSKVNKK
80
EVVEAVTIVE
90
TPPMVVVGIV
100
GYVETPRGLR
110
TFKTVFAEHI
120
SDECKRRFYK
130
NWHKSKKKAF
140
TKYCKKWQDD
150
TGKKQLEKDF
160
NSMKKYCQVI
170
RIIAHTQMRL
180
LPLRQKKAHL
190
MEIQVNGGTV
200
AEKLDWARER
210
LEQQVPVNQV
220
FGQDEMIDVI
230
GVTKGKGYKG
240
VTSRWHTKKL
250
PRKTHRGLRK
260
VACIGAWHPA
270
RVAFSVARAG
280
QKGYHHRTEI
290
NKKIYKIGQG
300
YLIKDGKLIK
310
NNASTDYDLS
320
DKSINPLGGF
330
VHYGEVTNDF
340
IMLKGCVVGT
350
KKRVLTLRKS
360
LLVQTKRRAL
370
EKIDLKFIDT
380
TSKFGHGRFQ
390
TMEEKKAFMG
400
PLKKDRIAKE
EGA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0022625 | cytosolic large ribosomal subunit |
| Cellular Component | GO:0022626 | cytosolic ribosome |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0032991 | protein-containing complex |
| Cellular Component | GO:0005840 | ribosome |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0008097 | 5S rRNA binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0003735 | structural constituent of ribosome |
| Biological Process | GO:0071353 | cellular response to interleukin-4 |
| Biological Process | GO:0002181 | cytoplasmic translation |
| Biological Process | GO:0006412 | translation |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.