Search Results
Overview
| Uniprot ID | P21550 |
|---|---|
| Protein Name | Beta-enolase |
| Gene Name | Eno3 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 126 | CKAGAAEKGVPLYRH |
| 193 | AEVYHHLKGVIKAKY |
| 256 | SEFYRNGKYDLDFKS |
| 262 | GKYDLDFKSPDDPAR |
| 275 | ARHISGEKLGELYKN |
| 28 | EVDLHTAKGRFRAAV |
| 334 | RIAQAVEKKACNCLL |
| 335 | IAQAVEKKACNCLLL |
| 343 | ACNCLLLKVNQIGSV |
| 420 | IEEALGDKAVFAGRK |
| 64 | YLGKGVLKAVEHINK |
| 71 | KAVEHINKTLGPALL |
| 80 | LGPALLEKKLSVVDQ |
| 81 | GPALLEKKLSVVDQE |
| 89 | LSVVDQEKVDKFMIE |
Function
Enolase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in glycolysis and the reverse reaction in gluconeogenesis. Appears to have a function in striated muscle development and regeneration
Protein Sequence
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0000015 | phosphopyruvate hydratase complex |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0000287 | magnesium ion binding |
| Molecular Function | GO:0004634 | phosphopyruvate hydratase activity |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Biological Process | GO:0061621 | canonical glycolysis |
| Biological Process | GO:0006096 | glycolytic process |
Reference
[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.
[2] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.
[3] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.