Search Results
Overview
| Uniprot ID | P21810 |
|---|---|
| Protein Name | Biglycan |
| Gene Name | BGN |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 111 | ELRKDDFKGLQHLYA |
| 132 | KISKIHEKAFSPLRK |
| 142 | SPLRKLQKLYISKNH |
| 219 | YLRISEAKLTGIPKD |
| 225 | AKLTGIPKDLPETLN |
| 240 | ELHLDHNKIQAIELE |
| 288 | ELHLDNNKLARVPSG |
| 328 | CPMGFGVKRAYYNGI |
| 82 | QCSDLGLKSVPKEIS |
| 86 | LGLKSVPKEISPDTT |
Function
May be involved in collagen fiber assembly
Protein Sequence
10
MWPLWRLVSL
20
LALSQALPFE
30
QRGFWDFTLD
40
DGPFMMNDEE
50
ASGADTSGVL
60
DPDSVTPTYS
70
AMCPFGCHCH
80
LRVVQCSDLG
90
LKSVPKEISP
100
DTTLLDLQNN
110
DISELRKDDF
120
KGLQHLYALV
130
LVNNKISKIH
140
EKAFSPLRKL
150
QKLYISKNHL
160
VEIPPNLPSS
170
LVELRIHDNR
180
IRKVPKGVFS
190
GLRNMNCIEM
200
GGNPLENSGF
210
EPGAFDGLKL
220
NYLRISEAKL
230
TGIPKDLPET
240
LNELHLDHNK
250
IQAIELEDLL
260
RYSKLYRLGL
270
GHNQIRMIEN
280
GSLSFLPTLR
290
ELHLDNNKLA
300
RVPSGLPDLK
310
LLQVVYLHSN
320
NITKVGVNDF
330
CPMGFGVKRA
340
YYNGISLFNN
350
PVPYWEVQPA
360
TFRCVTDRLA
IQFGNYKK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0009986 | cell surface |
| Cellular Component | GO:0071953 | elastic fiber |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0031012 | extracellular matrix |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0140150 | gel phase of interstitial matrix |
| Cellular Component | GO:0005796 | Golgi lumen |
| Cellular Component | GO:0043202 | lysosomal lumen |
| Cellular Component | GO:0042383 | sarcolemma |
| Cellular Component | GO:0030133 | transport vesicle |
| Molecular Function | GO:0019955 | cytokine binding |
| Molecular Function | GO:0050840 | extracellular matrix binding |
| Molecular Function | GO:0005201 | extracellular matrix structural constituent |
| Molecular Function | GO:0030021 | extracellular matrix structural constituent conferring compression resistance |
| Molecular Function | GO:0005539 | glycosaminoglycan binding |
| Biological Process | GO:0001974 | blood vessel remodeling |
Reference
[1] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.
[2] Yang YH, Wang QC, Kong J, Yang JT, Liu JF. Global profiling of lysine lactylation in human lungs.. Proteomics 23(15):e2200437. 2023 Aug. PMID: 37170646.
[3] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.