Search Results
Overview
| Uniprot ID | P24844 |
|---|---|
| Protein Name | Myosin regulatory light polypeptide 9 |
| Gene Name | MYL9 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 150 | YREAPIDKKGNFNYV |
| 151 | REAPIDKKGNFNYVE |
Function
Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (PubMed:11942626, PubMed:2526655). In myoblasts, may regulate PIEZO1-dependent cortical actomyosin assembly involved in myotube formation (By similarity)
Protein Sequence
10
MSSKRAKAKT
20
TKKRPQRATS
30
NVFAMFDQSQ
40
IQEFKEAFNM
50
IDQNRDGFID
60
KEDLHDMLAS
70
LGKNPTDEYL
80
EGMMSEAPGP
90
INFTMFLTMF
100
GEKLNGTDPE
110
DVIRNAFACF
120
DEEASGFIHE
130
DHLRELLTTM
140
GDRFTDEEVD
150
EMYREAPIDK
160
KGNFNYVEFT
170
RILKHGAKDK
DD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005938 | cell cortex |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005859 | muscle myosin complex |
| Cellular Component | GO:0030016 | myofibril |
| Cellular Component | GO:0016460 | myosin II complex |
| Cellular Component | GO:0001725 | stress fiber |
| Cellular Component | GO:0030018 | Z disc |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0032036 | myosin heavy chain binding |
| Molecular Function | GO:0005200 | structural constituent of cytoskeleton |
| Molecular Function | GO:0008307 | structural constituent of muscle |
| Biological Process | GO:0030239 | myofibril assembly |
| Biological Process | GO:0070527 | platelet aggregation |
| Biological Process | GO:0006937 | regulation of muscle contraction |
| Biological Process | GO:0043149 | stress fiber assembly |
Reference
[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.