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Overview

Uniprot IDP25886
Protein NameLarge ribosomal subunit protein eL29
Gene NameRpl29
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
103 LAFIAHPKLGKKIRS
140 APAKAQAKAPAQAPK
147 KAPAQAPKGAQAPVK
63 KMQANNAKAVSARAE
73 SARAEAIKALVKPQA
77 EAIKALVKPQAVKPK

Function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Protein Sequence

10 MAKSKNHTTH 20 NQSRKWHRNG 30 IKKPRSQRYE 40 SLKGVDPKFL 50 RNMRFAKKHN 60 KKGLKKMQAN 70 NAKAVSARAE 80 AIKALVKPQA 90 VKPKMPKGSS 100 RKLSRLAFIA 110 HPKLGKKIRS 120 YMAKGRRLCQ 130 PKPKVQTKAE 140 AKAPAKAQAK 150 APAQAPKGAQ APVKAP

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane
Cellular Component GO:0005829 cytosol
Cellular Component GO:0022625 cytosolic large ribosomal subunit
Cellular Component GO:0022626 cytosolic ribosome
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0015934 large ribosomal subunit
Cellular Component GO:0016020 membrane
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0005840 ribosome
Cellular Component GO:0045202 synapse
Molecular Function GO:0008201 heparin binding
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0031589 cell-substrate adhesion
Biological Process GO:0002181 cytoplasmic translation
Biological Process GO:0035264 multicellular organism growth
Biological Process GO:0006412 translation

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.

[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.