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Overview

Uniprot IDP26044
Protein NameRadixin
Gene NameRDX
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
327 RAQLENEKKKREIAE
64 TWLKLNKKVTQQDVK

Function

Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane

Protein Sequence

10 MPKPINVRVT 20 TMDAELEFAI 30 QPNTTGKQLF 40 DQVVKTVGLR 50 EVWFFGLQYV 60 DSKGYSTWLK 70 LNKKVTQQDV 80 KKENPLQFKF 90 RAKFFPEDVS 100 EELIQEITQR 110 LFFLQVKEAI 120 LNDEIYCPPE 130 TAVLLASYAV 140 QAKYGDYNKE 150 IHKPGYLAND 160 RLLPQRVLEQ 170 HKLTKEQWEE 180 RIQNWHEEHR 190 GMLREDSIME 200 YLKIAQDLEM 210 YGVNYFEIKN 220 KKGTELWLGV 230 DALGLNIYEH 240 DDKLTPKIGF 250 PWSEIRNISF 260 NDKKFVIKPI 270 DKKAPDFVFY 280 APRLRINKRI 290 LALCMGNHEL 300 YMRRRKPDTI 310 EVQQMKAQAR 320 EEKHQKQLER 330 AQLENEKKKR 340 EIAEKEKERI 350 EREKEELMER 360 LRQIEEQTMK 370 AQKELEEQTR 380 KALELDQERK 390 RAKEEAERLE 400 KERRAAEEAK 410 SAIAKQAADQ 420 MKNQEQLAAE 430 LAEFTAKIAL 440 LEEAKKKKEE 450 EATEWQHKAF 460 AAQEDLEKTK 470 EELKTVMSAP 480 PPPPPPPVVP 490 PTENEHDEHD 500 ENNAEASAEL 510 SNDGVMNHRS 520 EEERVTETQK 530 NERVNKQLQA 540 LSSELAQARD 550 ETKKTQNDVL 560 HAENVKAGRD 570 KYKTLRQIRQ 580 GNTKQRIDEF EAM

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005912 adherens junction
Cellular Component GO:0045177 apical part of cell
Cellular Component GO:0032154 cleavage furrow
Cellular Component GO:0005856 cytoskeleton
Cellular Component GO:0030175 filopodium
Cellular Component GO:0005902 microvillus
Cellular Component GO:0005886 plasma membrane
Cellular Component GO:0120044 stereocilium base
Molecular Function GO:0003779 actin binding
Molecular Function GO:0050839 cell adhesion molecule binding
Biological Process GO:0051693 actin filament capping
Biological Process GO:2000643 positive regulation of early endosome to late endosome transport
Biological Process GO:1902966 positive regulation of protein localization to early endosome
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:1902115 regulation of organelle assembly

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.