Search Results
Overview
| Uniprot ID | P26885 |
|---|---|
| Protein Name | Peptidyl-prolyl cis-trans isomerase FKBP2 |
| Gene Name | FKBP2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 103 | MCEGEKRKLVIPSEL |
| 30 | TGAEGKRKLQIGVKK |
Function
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Protein Sequence
10
MRLSWFRVLT
20
VLSICLSAVA
30
TATGAEGKRK
40
LQIGVKKRVD
50
HCPIKSRKGD
60
VLHMHYTGKL
70
EDGTEFDSSL
80
PQNQPFVFSL
90
GTGQVIKGWD
100
QGLLGMCEGE
110
KRKLVIPSEL
120
GYGERGAPPK
130
IPGGATLVFE
140
VELLKIERRT
EL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Molecular Function | GO:0005528 | FK506 binding |
| Molecular Function | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.