Search Results
Overview
| Uniprot ID | P27105 |
|---|---|
| Protein Name | Stomatin |
| Gene Name | STOM |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 220 | ASREARAKVIAAEGE |
Function
Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity
Protein Sequence
10
MAEKRHTRDS
20
EAQRLPDSFK
30
DSPSKGLGPC
40
GWILVAFSFL
50
FTVITFPISI
60
WMCIKIIKEY
70
ERAIIFRLGR
80
ILQGGAKGPG
90
LFFILPCTDS
100
FIKVDMRTIS
110
FDIPPQEILT
120
KDSVTISVDG
130
VVYYRVQNAT
140
LAVANITNAD
150
SATRLLAQTT
160
LRNVLGTKNL
170
SQILSDREEI
180
AHNMQSTLDD
190
ATDAWGIKVE
200
RVEIKDVKLP
210
VQLQRAMAAE
220
AEASREARAK
230
VIAAEGEMNA
240
SRALKEASMV
250
ITESPAALQL
260
RYLQTLTTIA
270
AEKNSTIVFP
280
LPIDMLQGII
GAKHSHLG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0035577 | azurophil granule membrane |
| Cellular Component | GO:0072562 | blood microparticle |
| Cellular Component | GO:0042470 | melanosome |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0045121 | membrane raft |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0035579 | specific granule membrane |
| Cellular Component | GO:0070821 | tertiary granule membrane |
| Cellular Component | GO:0031982 | vesicle |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0008200 | ion channel inhibitor activity |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0070063 | RNA polymerase binding |
| Biological Process | GO:0044829 | host-mediated activation of viral genome replication |
| Biological Process | GO:0090314 | positive regulation of protein targeting to membrane |
| Biological Process | GO:0048524 | positive regulation of viral process |
| Biological Process | GO:0034765 | regulation of monoatomic ion transmembrane transport |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.