Search Results

Overview

Uniprot IDP28290
Protein NameProtein ITPRID2
Gene NameITPRID2
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
1139 TASVGKSKTPLVARK
150 RRLQFHQKGRSMNST
301 RLMKTLSKLNLCVDK
701 ALQRAQMKVCSLSNQ
729 KQRYLFAKAGYPLRR

Function

No function data available.

Protein Sequence

10 MDRPLSSSAE 20 AEEELEWQVA 30 SRRRKAWAKC 40 RSSWQASETE 50 DLSTEATTQD 60 EEEDEEEDLP 70 GAQLPAAGGR 80 GNVPNEKIAI 90 WLKDCRTPLG 100 ASLDEQSSST 110 LKGVLVRNGG 120 SFEDDLSLGA 130 EANHLHESDA 140 QIENCNNILA 150 KERRLQFHQK 160 GRSMNSTGSG 170 KSSGTVSSVS 180 ELLELYEEDP 190 EEILYNLGFG 200 RDEPDIASKI 210 PSRFFNSSSF 220 AKGIDIKVFL 230 SAQMQRMEVE 240 NPNYALTSRF 250 RQIEVLTTVA 260 NAFSSLYSQV 270 SGTPLQRIGS 280 MSSVTSNKET 290 DPPPPLTRSN 300 TANRLMKTLS 310 KLNLCVDKTE 320 KGESSSPSPS 330 AEKGKILNVS 340 VIEESGNKND 350 QKSQKIMKKK 360 ESSSMLATVK 370 EEVSGSSAAV 380 TENADSDRIS 390 DEANSNFNQG 400 TENEQSKETQ 410 SHESKLGEES 420 GIVESKLDSD 430 FNISSHSELE 440 NSSELKSVHI 450 STPEKEPCAP 460 LTIPSIRNIM 470 TQQKDSFEME 480 EVQSTEGEAP 490 HVPATYQLGL 500 TKSKRDHLLR 510 TASQHSDSSG 520 FAEDSTDCLS 530 LNHLQVQESL 540 QAMGSSADSC 550 DSETTVTSLG 560 EDLATPTAQD 570 QPYFNESEEE 580 SLVPLQKGLE 590 KAAAVADKRK 600 SGSQDFPQCN 610 TIENTGTKQS 620 TCSPGDHIIE 630 ITEVEEDLFP 640 AETVELLREA 650 SAESDVGKSS 660 ESEFTQYTTH 670 HILKSLASIE 680 AKCSDMSSEN 690 TTGPPSSMDR 700 VNTALQRAQM 710 KVCSLSNQRM 720 GRSLLKSKDL 730 LKQRYLFAKA 740 GYPLRRSQSL 750 PTTLLSPVRV 760 VSSVNVRLSP 770 GKETRCSPPS 780 FTYKYTPEEE 790 QELEKRVMEH 800 DGQSLVKSTI 810 FISPSSVKKE 820 EAPQSEAPRV 830 EECHHGRTPT 840 CSRLAPPPMS 850 QSTCSLHSIH 860 SEWQERPLCE 870 HTRTLSTHSV 880 PNISGATCSA 890 FASPFGCPYS 900 HRHATYPYRV 910 CSVNPPSAIE 920 MQLRRVLHDI 930 RNSLQNLSQY 940 PMMRGPDPAA 950 APYSTQKSSV 960 LPLYENTFQE 970 LQVMRRSLNL 980 FRTQMMDLEL 990 AMLRQQTMVY 1000 HHMTEEERFE 1010 VDQLQGLRNS 1020 VRMELQDLEL 1030 QLEERLLGLE 1040 EQLRAVRMPS 1050 PFRSSALMGM 1060 CGSRSADNLS 1070 CPSPLNVMEP 1080 VTELMQEQSY 1090 LKSELGLGLG 1100 EMGFEIPPGE 1110 SSESVFSQAT 1120 SESSSVCSGP 1130 SHANRRTGVP 1140 STASVGKSKT 1150 PLVARKKVFR 1160 ASVALTPTAP 1170 SRTGSVQTPP 1180 DLESSEEVDA 1190 AEGAPEVVGP 1200 KSEVEEGHGK 1210 LPSMPAAEEM 1220 HKNVEQDELQ 1230 QVIREIKESI 1240 VGEIRREIVS 1250 GLLAAVSSSK ASNSKQDYH

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0051015 actin filament binding
Molecular Function GO:0005102 signaling receptor binding

Reference

[1] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.

[2] Bao Q, Wan N, He Z, Cao J, Yuan W et al.. Subcellular Proteomic Mapping of Lysine Lactylation.. J Am Soc Mass Spectrom 35(12):3221-3232. 2024 Dec 4. PMID: 39569522.

[3] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.

[4] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.