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Overview

Uniprot IDP29269
Protein NameMyosin regulatory light polypeptide 9
Gene NameMYL9
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
150 YREAPIDKKGNFNYV
164 VEFTRILKHGAKDKD

Function

Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity). In myoblasts, may regulate PIEZO1-dependent cortical actomyosin assembly involved in myotube formation (By similarity)

Protein Sequence

10 MSSKRAKAKT 20 TKKRPQRATS 30 NVFAMFDQSQ 40 IQEFKEAFNM 50 IDQNRDGFID 60 KEDLHDMLAS 70 LGKNPTDEYL 80 EGMMSEAPGP 90 INFTMFLTMF 100 GEKLNGTDPE 110 DVIRNAFACF 120 DEEASGFIHE 130 DHLRELLTTM 140 GDRFTDEEVD 150 EMYREAPIDK 160 KGNFNYVEFT 170 RILKHGAKDK DD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005938 cell cortex
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0030016 myofibril
Cellular Component GO:0016460 myosin II complex
Cellular Component GO:0001725 stress fiber
Molecular Function GO:0005509 calcium ion binding
Molecular Function GO:0032036 myosin heavy chain binding
Biological Process GO:0030239 myofibril assembly

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.