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Overview

Uniprot IDP29373
Protein NameCellular retinoic acid-binding protein 2
Gene NameCRABP2
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
31 GVNVMLRKIAVAAAS
83 TVDGRPCKSLVKWES

Function

Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors

Protein Sequence

10 MPNFSGNWKI 20 IRSENFEELL 30 KVLGVNVMLR 40 KIAVAAASKP 50 AVEIKQEGDT 60 FYIKTSTTVR 70 TTEINFKVGE 80 EFEEQTVDGR 90 PCKSLVKWES 100 ENKMVCEQKL 110 LKGEGPKTSW 120 TRELTNDGEL 130 ILTMTADDVV CTRVYVRE

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0070062 extracellular exosome
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Molecular Function GO:0030332 cyclin binding
Molecular Function GO:0005504 fatty acid binding
Molecular Function GO:0016918 retinal binding
Molecular Function GO:0001972 retinoic acid binding
Molecular Function GO:0005501 retinoid binding
Molecular Function GO:0019841 retinol binding
Biological Process GO:0008544 epidermis development
Biological Process GO:0015908 fatty acid transport
Biological Process GO:0006355 regulation of DNA-templated transcription
Biological Process GO:0007165 signal transduction

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.