Search Results
Overview
| Uniprot ID | P30711 |
|---|---|
| Protein Name | Glutathione S-transferase theta-1 |
| Gene Name | GSTT1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 52 | FAQVNPLKKVPALKD |
Function
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide
Protein Sequence
10
MGLELYLDLL
20
SQPCRAVYIF
30
AKKNDIPFEL
40
RIVDLIKGQH
50
LSDAFAQVNP
60
LKKVPALKDG
70
DFTLTESVAI
80
LLYLTRKYKV
90
PDYWYPQDLQ
100
ARARVDEYLA
110
WQHTTLRRSC
120
LRALWHKVMF
130
PVFLGEPVSP
140
QTLAATLAEL
150
DVTLQLLEDK
160
FLQNKAFLTG
170
PHISLADLVA
180
ITELMHPVGA
190
GCQVFEGRPK
200
LATWRQRVEA
210
AVGEDLFQEA
220
HEVILKAKDF
230
PPADPTIKQK
240
LMPWVLAMIR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0070062 | extracellular exosome |
| Molecular Function | GO:0004602 | glutathione peroxidase activity |
| Molecular Function | GO:0004364 | glutathione transferase activity |
| Biological Process | GO:0006749 | glutathione metabolic process |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.