Search Results

Overview

Uniprot IDP31232
Protein NameTransgelin
Gene NameTagln
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
154 GDPNWFMKKAQEHKR
17 MSREVQSKIEKKYDE
21 VQSKIEKKYDEELEE
4 ****MANKGPSYGMS
75 SLYPEGSKPVKVPEN
78 PEGSKPVKVPENPPS

Function

Actin cross-linking/gelling protein

Protein Sequence

10 MANKGPSYGM 20 SREVQSKIEK 30 KYDEELEERL 40 VEWIVMQCGP 50 DVGRPDRGRL 60 GFQVWLKNGV 70 ILSKLVNSLY 80 PEGSKPVKVP 90 ENPPSMVFKQ 100 MEQVAQFLKA 110 AEDYGVTKTD 120 MFQTVDLFEG 130 KDMAAVQRTV 140 MALGSLAVTK 150 NDGHYRGDPN 160 WFMKKAQEHK 170 REFTDSQLQE 180 GKHVIGLQMG 190 SNRGASQAGM 200 TGYGRPRQII S

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Molecular Function GO:0051015 actin filament binding
Molecular Function GO:0030674 protein-macromolecule adaptor activity
Biological Process GO:0036120 cellular response to platelet-derived growth factor stimulus
Biological Process GO:0030855 epithelial cell differentiation

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.

[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.