Search Results
Overview
| Uniprot ID | P31662 |
|---|---|
| Protein Name | Sodium-dependent neutral amino acid transporter SLC6A17 |
| Gene Name | Slc6a17 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 47 | VAGETGGKQKVAEEE |
| 662 | YKKGRMMKDISNLEE |
Function
Synaptic vesicle transporter with apparent selectivity for neutral amino acids. The transport is sodium-coupled but chloride-independent, likely driven by the proton electrochemical gradient generated by vacuolar H(+)-ATPase in an overall electrogenic mechanism. May contribute to the synaptic uptake of neurotransmitter precursors in a process coupled in part to vesicle exocytosis
Protein Sequence
10
MPKNSKVTQR
20
EHSNEHVTES
30
VADLLALEEP
40
VDYKQSVLNV
50
AGETGGKQKV
60
AEEELDAEDR
70
PAWNSKLQYI
80
LAQIGFSVGL
90
GNIWRFPYLC
100
QKNGGGAYLV
110
PYLVLLIIIG
120
IPLFFLELAV
130
GQRIRRGSIG
140
VWHYVCPRLG
150
GIGFSSCIVC
160
LFVGLYYNVI
170
IGWSVFYFFK
180
SFQYPLPWSE
190
CPVIRNGTVA
200
VVEPECEKSS
210
ATTYFWYREA
220
LDISNSISES
230
GGLNWKMTVC
240
LLVAWSIVGM
250
AVVKGIQSSG
260
KVMYFSSLFP
270
YVVLACFLVR
280
GLLLRGAVDG
290
ILHMFTPKLD
300
KMLDPQVWRE
310
AATQVFFALG
320
LGFGGVIAFS
330
SYNKQDNNCH
340
FDAALVSFIN
350
FFTSVLATLV
360
VFAVLGFKAN
370
IMNEKCVVEN
380
AEKILGYLNS
390
NVLSRDLIPP
400
HVNFSHLTTK
410
DYSEMYNVIM
420
TVKEKQFSAL
430
GLDPCLLEDE
440
LDKSVQGTGL
450
AFIAFTEAMT
460
HFPASPFWSV
470
MFFLMLINLG
480
LGSMIGTMAG
490
ITTPIIDTFK
500
VPKEMFTVGC
510
CVFAFFVGLL
520
FVQRSGNYFV
530
TMFDDYSATL
540
PLTVIVILEN
550
IAVAWIYGTK
560
KFMQELTEML
570
GFRPYRFYFY
580
MWKFVSPLCM
590
AVLTTASIIQ
600
LGVSPPGYSA
610
WIKEEAAERY
620
LYFPNWAMAL
630
LITLIAVATL
640
PIPVVFILRH
650
FHLLSDGSNT
660
LSVSYKKGRM
670
MKDISNLEEN
680
DETRFILSKV
690
PSEAPSPMPT
700
HRSYLGPGST
710
SPLESSSHPN
720
GRYGSGYLLA
STPESEL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0006836 | neurotransmitter transport |
| Cellular Component | GO:0098982 | GABA-ergic synapse |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0098794 | postsynapse |
| Cellular Component | GO:0045202 | synapse |
| Cellular Component | GO:0008021 | synaptic vesicle |
| Cellular Component | GO:0030672 | synaptic vesicle membrane |
| Molecular Function | GO:0015293 | symporter activity |
| Biological Process | GO:0032328 | alanine transport |
| Biological Process | GO:0007420 | brain development |
| Biological Process | GO:0015816 | glycine transport |
| Biological Process | GO:0015820 | L-leucine transport |
| Biological Process | GO:0015804 | neutral amino acid transport |
| Biological Process | GO:0015824 | proline transport |
| Biological Process | GO:0030163 | protein catabolic process |
| Biological Process | GO:0035725 | sodium ion transmembrane transport |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.