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Overview

Uniprot IDP31691
Protein NameADP/ATP translocase, mitochondrial
Gene NameOs02g0718900
OrganismOryza sativa subsp. japonica

Kla Sites from experimental identification

Position Flanking peptide
118 QNQDEMIKAGRLSEP

Function

ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity). Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity)

Protein Sequence

10 MAEQANQPTV 20 LQKFGGQFHL 30 GSSFSEGVRA 40 RNICPSVSSY 50 DRRFTTRSYM 60 TQGLVNGGIN 70 VPMMSSSPIF 80 ANAPAEKGGK 90 NFMIDFLMGG 100 VSAAVSKTAA 110 APIERVKLLI 120 QNQDEMIKAG 130 RLSEPYKGIG 140 DCFGRTIKDE 150 GFASLWRGNT 160 ANVIRYFPTQ 170 ALNFAFKDYF 180 KRLFNFKKDK 190 DGYWKWFGGN 200 LASGGAAGAS 210 SLFFVYSLDY 220 ARTRLANDAK 230 AAKGGGERQF 240 NGLVDVYRKT 250 LKSDGIAGLY 260 RGFNISCVGI 270 IVYRGLYFGM 280 YDSLKPVVLT 290 GSLQDNFFAS 300 FALGWLITNG 310 AGLASYPIDT 320 VRRRMMMTSG 330 EAVKYKSSMD 340 AFSQILKNEG 350 AKSLFKGAGA 360 NILRAIAGAG 370 VLSGYDQLQI 380 LFFGKKYGSG GA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005757 mitochondrial permeability transition pore complex
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0005471 ATP:ADP antiporter activity
Biological Process GO:0140021 mitochondrial ADP transmembrane transport
Biological Process GO:1990544 mitochondrial ATP transmembrane transport
Biological Process GO:0046902 regulation of mitochondrial membrane permeability

Reference

[1] Meng X, Baine JM, Yan T, Wang S. Comprehensive Analysis of Lysine Lactylation in Rice (Oryza sativa) Grains.. J Agric Food Chem 69(29):8287-8297. 2021 Jul 28. PMID: 34264677.