Search Results
Overview
| Uniprot ID | P31937 |
|---|---|
| Protein Name | 3-hydroxyisobutyrate dehydrogenase, mitochondrial |
| Gene Name | HIBADH |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 125 | GILKKVKKGSLLIDS |
| 145 | AVSKELAKEVEKMGA |
| 149 | ELAKEVEKMGAVFMD |
| 242 | LDPKLLAKILNMSSG |
| 321 | CAKGYSKKDFSSVFQ |
| 76 | DVFPDACKEFQDAGE |
| 95 | SPADVAEKADRIITM |
Function
No function data available.
Protein Sequence
10
MAASLRLLGA
20
ASGLRYWSRR
30
LRPAAGSFAA
40
VCSRSVASKT
50
PVGFIGLGNM
60
GNPMAKNLMK
70
HGYPLIIYDV
80
FPDACKEFQD
90
AGEQVVSSPA
100
DVAEKADRII
110
TMLPTSINAI
120
EAYSGANGIL
130
KKVKKGSLLI
140
DSSTIDPAVS
150
KELAKEVEKM
160
GAVFMDAPVS
170
GGVGAARSGN
180
LTFMVGGVED
190
EFAAAQELLG
200
CMGSNVVYCG
210
AVGTGQAAKI
220
CNNMLLAISM
230
IGTAEAMNLG
240
IRLGLDPKLL
250
AKILNMSSGR
260
CWSSDTYNPV
270
PGVMDGVPSA
280
NNYQGGFGTT
290
LMAKDLGLAQ
300
DSATSTKSPI
310
LLGSLAHQIY
320
RMMCAKGYSK
330
KDFSSVFQFL
REEETF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0008442 | 3-hydroxyisobutyrate dehydrogenase activity |
| Molecular Function | GO:0051287 | NAD binding |
| Molecular Function | GO:0050661 | NADP binding |
| Biological Process | GO:0006574 | L-valine catabolic process |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.