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Overview

Uniprot IDP32736
Protein NameOpioid-binding protein/cell adhesion molecule
Gene NameOpcml
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
230 PPYISKAKNTGVSVG

Function

Binds opioids in the presence of acidic lipids; probably involved in cell contact

Protein Sequence

10 MGVCGYLFLP 20 WKCLVVVSLR 30 LLFLVPTGVP 40 VRSGDATFPK 50 AMDNVTVRQG 60 ESATLRCTID 70 DRVTRVAWLN 80 RSTILYAGND 90 KWSIDPRVII 100 LVNTPTQYSI 110 MIQNVDVYDE 120 GPYTCSVQTD 130 NHPKTSRVHL 140 IVQVPPQIMN 150 ISSDITVNEI 160 SSVTLLCLAI 170 GRPEPTVTWR 180 HLSVKEGQGF 190 VSEDEYLEIS 200 DIKRDQSGEY 210 ECSALNDVAA 220 PDVRKVKITV 230 NYPPYISKAK 240 NTGVSVGQKG 250 ILSCEASAVP 260 MAEFQWFKED 270 TRLATGLDGV 280 RIENKGRIST 290 LTFFNVSEKD 300 YGNYTCVATN 310 KLGNTNASIT 320 LYGPGAVIDG 330 VNSASRALAC 340 LWLSGTFFAH FFIKF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0097440 apical dendrite
Cellular Component GO:0043197 dendritic spine
Cellular Component GO:0043025 neuronal cell body
Cellular Component GO:0005886 plasma membrane
Cellular Component GO:0014069 postsynaptic density
Cellular Component GO:0098552 side of membrane
Biological Process GO:0007157 heterophilic cell-cell adhesion
Biological Process GO:0060253 negative regulation of glial cell proliferation
Biological Process GO:0045793 positive regulation of cell size
Biological Process GO:0051965 positive regulation of synapse assembly
Biological Process GO:0051963 regulation of synapse assembly

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.