Search Results
Overview
| Uniprot ID | P33240 |
|---|---|
| Protein Name | Cleavage stimulation factor subunit 2 |
| Gene Name | CSTF2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 572 | ILKEQIQKSTGAP** |
Function
One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs
Protein Sequence
10
MAGLTVRDPA
20
VDRSLRSVFV
30
GNIPYEATEE
40
QLKDIFSEVG
50
PVVSFRLVYD
60
RETGKPKGYG
70
FCEYQDQETA
80
LSAMRNLNGR
90
EFSGRALRVD
100
NAASEKNKEE
110
LKSLGTGAPV
120
IESPYGETIS
130
PEDAPESISK
140
AVASLPPEQM
150
FELMKQMKLC
160
VQNSPQEARN
170
MLLQNPQLAY
180
ALLQAQVVMR
190
IVDPEIALKI
200
LHRQTNIPTL
210
IAGNPQPVHG
220
AGPGSGSNVS
230
MNQQNPQAPQ
240
AQSLGGMHVN
250
GAPPLMQASM
260
QGGVPAPGQM
270
PAAVTGPGPG
280
SLAPGGGMQA
290
QVGMPGSGPV
300
SMERGQVPMQ
310
DPRAAMQRGS
320
LPANVPTPRG
330
LLGDAPNDPR
340
GGTLLSVTGE
350
VEPRGYLGPP
360
HQGPPMHHVP
370
GHESRGPPPH
380
ELRGGPLPEP
390
RPLMAEPRGP
400
MLDQRGPPLD
410
GRGGRDPRGI
420
DARGMEARAM
430
EARGLDARGL
440
EARAMEARAM
450
EARAMEARAM
460
EARAMEVRGM
470
EARGMDTRGP
480
VPGPRGPIPS
490
GMQGPSPINM
500
GAVVPQGSRQ
510
VPVMQGTGMQ
520
GASIQGGSQP
530
GGFSPGQNQV
540
TPQDHEKAAL
550
IMQVLQLTAD
560
QIAMLPPEQR
570
QSILILKEQI
QKSTGAP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0071920 | cleavage body |
| Cellular Component | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex |
| Cellular Component | GO:0016604 | nuclear body |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:1990090 | cellular response to nerve growth factor stimulus |
| Biological Process | GO:0031124 | mRNA 3'-end processing |
| Biological Process | GO:0071045 | nuclear histone mRNA catabolic process |
| Biological Process | GO:0031440 | regulation of mRNA 3'-end processing |
Reference
PMID: N/A