Search Results

Overview

Uniprot IDP33432
Protein NamePuroindoline-A
Gene NamePINA
OrganismTriticum aestivum

Kla Sites from experimental identification

Position Flanking peptide
120 FQRDRASKVIQEAKN

Function

Acts as a membranotoxin, probably through its antibacterial and antifungal activities, contributing to the defense mechanism of the plant against predators. Forms monovalent cation-selective ion channels in membranes. Has antibacterial activity against the Gram-positive bacteria S.aureus and C.michiganensis, and the Gram-negative bacteria E.coli, P.syringae pv phaseoli, A.tumefaciens and E.carotovora subsp carotovora. Acts synergistically with PINB against bacteria. Contributes to grain texture and hardness

Protein Sequence

10 MKALFLIGLL 20 ALVASTAFAQ 30 YSEVVGSYDV 40 AGGGGAQQCP 50 VETKLNSCRN 60 YLLDRCSTMK 70 DFPVTWRWWK 80 WWKGGCQELL 90 GECCSRLGQM 100 PPQCRCNIIQ 110 GSIQGDLGGI 120 FGFQRDRASK 130 VIQEAKNLPP 140 RCNQGPPCNI PGTIGYYW

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005576 extracellular region
Cellular Component GO:0016020 membrane
Molecular Function GO:0045735 nutrient reservoir activity
Molecular Function GO:0090729 toxin activity
Biological Process GO:0042742 defense response to bacterium

Reference

[1] Zhu J, Guo W, Lan Y. Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.. Int J Mol Sci 24(22). 2023 Nov 11. PMID: 38003390.