Search Results
Overview
| Uniprot ID | P35030 |
|---|---|
| Protein Name | Trypsin-3 |
| Gene Name | PRSS3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 149 | EQFINAAKIIRHPKY |
Function
Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors
Protein Sequence
10
MCGPDDRCPA
20
RWPGPGRAVK
30
CGKGLAAARP
40
GRVERGGAQR
50
GGAGLELHPL
60
LGGRTWRAAR
70
DADGCEALGT
80
VAVPFDDDDK
90
IVGGYTCEEN
100
SLPYQVSLNS
110
GSHFCGGSLI
120
SEQWVVSAAH
130
CYKTRIQVRL
140
GEHNIKVLEG
150
NEQFINAAKI
160
IRHPKYNRDT
170
LDNDIMLIKL
180
SSPAVINARV
190
STISLPTTPP
200
AAGTECLISG
210
WGNTLSFGAD
220
YPDELKCLDA
230
PVLTQAECKA
240
SYPGKITNSM
250
FCVGFLEGGK
260
DSCQRDSGGP
270
VVCNGQLQGV
280
VSWGHGCAWK
290
NRPGVYTKVY
300
NYVDWIKDTI
AANS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:1904724 | tertiary granule lumen |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0004252 | serine-type endopeptidase activity |
| Molecular Function | GO:0008236 | serine-type peptidase activity |
| Biological Process | GO:0019730 | antimicrobial humoral response |
| Biological Process | GO:0007586 | digestion |
| Biological Process | GO:0043542 | endothelial cell migration |
| Biological Process | GO:0006508 | proteolysis |
| Biological Process | GO:0031638 | zymogen activation |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.