Search Results
Overview
| Uniprot ID | P35250 |
|---|---|
| Protein Name | Replication factor C subunit 2 |
| Gene Name | RFC2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 208 | RLMNVIEKERVPYTD |
Function
Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA (PubMed:9488738). This subunit binds ATP (By similarity)
Protein Sequence
10
MEVEAVCGGA
20
GEVEAQDSDP
30
APAFSKAPGS
40
AGHYELPWVE
50
KYRPVKLNEI
60
VGNEDTVSRL
70
EVFAREGNVP
80
NIIIAGPPGT
90
GKTTSILCLA
100
RALLGPALKD
110
AMLELNASND
120
RGIDVVRNKI
130
KMFAQQKVTL
140
PKGRHKIIIL
150
DEADSMTDGA
160
QQALRRTMEI
170
YSKTTRFALA
180
CNASDKIIEP
190
IQSRCAVLRY
200
TKLTDAQILT
210
RLMNVIEKER
220
VPYTDDGLEA
230
IIFTAQGDMR
240
QALNNLQSTF
250
SGFGFINSEN
260
VFKVCDEPHP
270
LLVKEMIQHC
280
VNANIDEAYK
290
ILAHLWHLGY
300
SPEDIIGNIF
310
RVCKTFQMAE
320
YLKLEFIKEI
330
GYTHMKIAEG
340
VNSLLQMAGL
350
LARLCQKTMA
PVAS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0006260 | DNA replication |
| Cellular Component | GO:0031390 | Ctf18 RFC-like complex |
| Cellular Component | GO:0005663 | DNA replication factor C complex |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0019899 | enzyme binding |
| Biological Process | GO:0006281 | DNA repair |
| Biological Process | GO:0000076 | DNA replication checkpoint signaling |
| Biological Process | GO:0006261 | DNA-templated DNA replication |
| Biological Process | GO:1900264 | positive regulation of DNA-directed DNA polymerase activity |
Reference
PMID: N/A