Search Results
Overview
| Uniprot ID | P35611 |
|---|---|
| Protein Name | Alpha-adducin |
| Gene Name | ADD1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 471 | SSPKSKTKWTKEDGH |
Function
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin
Protein Sequence
10
MNGDSRAAVV
20
TSPPPTTAPH
30
KERYFDRVDE
40
NNPEYLRERN
50
MAPDLRQDFN
60
MMEQKKRVSM
70
ILQSPAFCEE
80
LESMIQEQFK
90
KGKNPTGLLA
100
LQQIADFMTT
110
NVPNVYPAAP
120
QGGMAALNMS
130
LGMVTPVNDL
140
RGSDSIAYDK
150
GEKLLRCKLA
160
AFYRLADLFG
170
WSQLIYNHIT
180
TRVNSEQEHF
190
LIVPFGLLYS
200
EVTASSLVKI
210
NLQGDIVDRG
220
STNLGVNQAG
230
FTLHSAIYAA
240
RPDVKCVVHI
250
HTPAGAAVSA
260
MKCGLLPISP
270
EALSLGEVAY
280
HDYHGILVDE
290
EEKVLIQKNL
300
GPKSKVLILR
310
NHGLVSVGES
320
VEEAFYYIHN
330
LVVACEIQVR
340
TLASAGGPDN
350
LVLLNPEKYK
360
AKSRSPGSPV
370
GEGTGSPPKW
380
QIGEQEFEAL
390
MRMLDNLGYR
400
TGYPYRYPAL
410
REKSKKYSDV
420
EVPASVTGYS
430
FASDGDSGTC
440
SPLRHSFQKQ
450
QREKTRWLNS
460
GRGDEASEEG
470
QNGSSPKSKT
480
KWTKEDGHRT
490
STSAVPNLFV
500
PLNTNPKEVQ
510
EMRNKIREQN
520
LQDIKTAGPQ
530
SQVLCGVVMD
540
RSLVQGELVT
550
ASKAIIEKEY
560
QPHVIVSTTG
570
PNPFTTLTDR
580
ELEEYRREVE
590
RKQKGSEENL
600
DEAREQKEKS
610
PPDQPAVPHP
620
PPSTPIKLEE
630
DLVPEPTTGD
640
DSDAATFKPT
650
LPDLSPDEPS
660
EALGFPMLEK
670
EEEAHRPPSP
680
TEAPTEASPE
690
PAPDPAPVAE
700
EAAPSAVEEG
710
AAADPGSDGS
720
PGKSPSKKKK
730
KFRTPSFLKK
SKKKSDS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005912 | adherens junction |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0008290 | F-actin capping protein complex |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:0014731 | spectrin-associated cytoskeleton |
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0045296 | cadherin binding |
| Molecular Function | GO:0005516 | calmodulin binding |
| Molecular Function | GO:0008093 | cytoskeletal anchor activity |
| Molecular Function | GO:0046983 | protein dimerization activity |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0061629 | RNA polymerase II-specific DNA-binding transcription factor binding |
| Molecular Function | GO:0030507 | spectrin binding |
| Biological Process | GO:0030036 | actin cytoskeleton organization |
| Biological Process | GO:0051017 | actin filament bundle assembly |
| Biological Process | GO:0051016 | barbed-end actin filament capping |
| Biological Process | GO:0071277 | cellular response to calcium ion |
| Biological Process | GO:1903393 | positive regulation of adherens junction organization |
| Biological Process | GO:1903142 | positive regulation of establishment of endothelial barrier |
| Biological Process | GO:0030833 | regulation of actin filament polymerization |
Reference
PMID: N/A