Search Results
Overview
| Uniprot ID | P40124 |
|---|---|
| Protein Name | Adenylyl cyclase-associated protein 1 |
| Gene Name | Cap1 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 286 | THKNPALKAQSGPVR |
Function
Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity
Protein Sequence
10
MADMQNLVER
20
LERAVGRLEA
30
VSHTSDMHCG
40
YGDSPSKGAV
50
PYVQAFDSLL
60
ANPVAEYLKM
70
SKEIGGDVQK
80
HAEMVHTGLK
90
LERALLATAS
100
QCQQPAGNKL
110
SDLLAPISEQ
120
IQEVITFREK
130
NRGSKFFNHL
140
SAVSESIQAL
150
GWVALAAKPG
160
PFVKEMNDAA
170
MFYTNRVLKE
180
YRDVDKKHVD
190
WVRAYLSIWT
200
ELQAYIKEFH
210
TTGLAWSKTG
220
PVAKELSGLP
230
SGPSVGSGPP
240
PPPPGPPPPP
250
ISTSSGSDDS
260
ASRSALFAQI
270
NQGESITHAL
280
KHVSDDMKTH
290
KNPALKAQSG
300
PVRSGPKPFS
310
APKPQTSPSP
320
KPATKKEPAL
330
LELEGKKWRV
340
ENQENVSNLV
350
IDDTELKQVA
360
YIYKCVNTTL
370
QIKGKINSIT
380
VDNCKKLGLV
390
FDDVVGIVEI
400
INSRDVKVQV
410
MGKVPTISIN
420
KTDGCHAYLS
430
KNSLDCEIVS
440
AKSSEMNVLI
450
PTEGGDFNEF
460
PVPEQFKTLW
470
NGQKLVTTVT
EIAG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030864 | cortical actin cytoskeleton |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0098794 | postsynapse |
| Cellular Component | GO:0098793 | presynapse |
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0008179 | adenylate cyclase binding |
| Biological Process | GO:0030036 | actin cytoskeleton organization |
| Biological Process | GO:0007015 | actin filament organization |
| Biological Process | GO:0001667 | ameboidal-type cell migration |
| Biological Process | GO:0000902 | cell morphogenesis |
| Biological Process | GO:0098885 | modification of postsynaptic actin cytoskeleton |
| Biological Process | GO:0006898 | receptor-mediated endocytosis |
Reference
[1] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.