Search Results
Overview
| Uniprot ID | P40425 |
|---|---|
| Protein Name | Pre-B-cell leukemia transcription factor 2 |
| Gene Name | PBX2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 308 | RYKKNIGKFQEEANI |
Function
Transcriptional activator that binds the sequence 5'-ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1
Protein Sequence
10
MDERLLGPPP
20
PGGGRGGLGL
30
VSGEPGGPGE
40
PPGGGDPGGG
50
SGGVPGGRGK
60
QDIGDILQQI
70
MTITDQSLDE
80
AQAKKHALNC
90
HRMKPALFSV
100
LCEIKEKTGL
110
SIRSSQEEEP
120
VDPQLMRLDN
130
MLLAEGVAGP
140
EKGGGSAAAA
150
AAAAASGGGV
160
SPDNSIEHSD
170
YRSKLAQIRH
180
IYHSELEKYE
190
QACNEFTTHV
200
MNLLREQSRT
210
RPVAPKEMER
220
MVSIIHRKFS
230
AIQMQLKQST
240
CEAVMILRSR
250
FLDARRKRRN
260
FSKQATEVLN
270
EYFYSHLSNP
280
YPSEEAKEEL
290
AKKCGITVSQ
300
VSNWFGNKRI
310
RYKKNIGKFQ
320
EEANIYAVKT
330
AVSVTQGGHS
340
RTSSPTPPSS
350
AGSGGSFNLS
360
GSGDMFLGMP
370
GLNGDSYSAS
380
QVESLRHSMG
390
PGGYGDNLGG
400
GQMYSPREMR
410
ANGSWQEAVT
420
PSSVTSPTEG
430
PGSVHSDTSN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005667 | transcription regulator complex |
| Molecular Function | GO:0003682 | chromatin binding |
| Molecular Function | GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Molecular Function | GO:0140297 | DNA-binding transcription factor binding |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Molecular Function | GO:0000977 | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| Biological Process | GO:0009887 | animal organ morphogenesis |
| Biological Process | GO:0007420 | brain development |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0048568 | embryonic organ development |
| Biological Process | GO:0001654 | eye development |
| Biological Process | GO:0048666 | neuron development |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
Reference
PMID: N/A