Search Results
Overview
| Uniprot ID | P40937 |
|---|---|
| Protein Name | Replication factor C subunit 5 |
| Gene Name | RFC5 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 16 | QEQPAATKIRNLPWV |
Function
Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA
Protein Sequence
10
METSALKQQE
20
QPAATKIRNL
30
PWVEKYRPQT
40
LNDLISHQDI
50
LSTIQKFINE
60
DRLPHLLLYG
70
PPGTGKTSTI
80
LACAKQLYKD
90
KEFGSMVLEL
100
NASDDRGIDI
110
IRGPILSFAS
120
TRTIFKKGFK
130
LVILDEADAM
140
TQDAQNALRR
150
VIEKFTENTR
160
FCLICNYLSK
170
IIPALQSRCT
180
RFRFGPLTPE
190
LMVPRLEHVV
200
EEEKVDISED
210
GMKALVTLSS
220
GDMRRALNIL
230
QSTNMAFGKV
240
TEETVYTCTG
250
HPLKSDIANI
260
LDWMLNQDFT
270
TAYRNITELK
280
TLKGLALHDI
290
LTEIHLFVHR
300
VDFPSSVRIH
310
LLTKMADIEY
320
RLSVGTNEKI
330
QLSSLIAAFQ
340
VTRDLIVAEA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0031390 | Ctf18 RFC-like complex |
| Cellular Component | GO:0005663 | DNA replication factor C complex |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0019899 | enzyme binding |
| Biological Process | GO:0006281 | DNA repair |
| Biological Process | GO:0006260 | DNA replication |
| Biological Process | GO:0000076 | DNA replication checkpoint signaling |
| Biological Process | GO:0006261 | DNA-templated DNA replication |
| Biological Process | GO:1900264 | positive regulation of DNA-directed DNA polymerase activity |
Reference
PMID: N/A