Search Results
Overview
| Uniprot ID | P41208 |
|---|---|
| Protein Name | Centrin-2 |
| Gene Name | CETN2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 108 | DTKEEILKAFKLFDD |
| 7 | *MASNFKKANMASSS |
Function
Plays a fundamental role in microtubule organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CCP110
Protein Sequence
10
MASNFKKANM
20
ASSSQRKRMS
30
PKPELTEEQK
40
QEIREAFDLF
50
DADGTGTIDV
60
KELKVAMRAL
70
GFEPKKEEIK
80
KMISEIDKEG
90
TGKMNFGDFL
100
TVMTQKMSEK
110
DTKEEILKAF
120
KLFDDDETGK
130
ISFKNLKRVA
140
KELGENLTDE
150
ELQEMIDEAD
160
RDGDGEVSEQ
170
EFLRIMKKTS
LY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0045177 | apical part of cell |
| Cellular Component | GO:0005814 | centriole |
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0036064 | ciliary basal body |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0044615 | nuclear pore nuclear basket |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0032391 | photoreceptor connecting cilium |
| Cellular Component | GO:0097225 | sperm midpiece |
| Cellular Component | GO:0097228 | sperm principal piece |
| Cellular Component | GO:0070390 | transcription export complex 2 |
| Cellular Component | GO:0071942 | XPC complex |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0031683 | G-protein beta/gamma-subunit complex binding |
| Molecular Function | GO:0032795 | heterotrimeric G-protein binding |
| Molecular Function | GO:0008017 | microtubule binding |
| Biological Process | GO:0051301 | cell division |
| Biological Process | GO:0007099 | centriole replication |
| Biological Process | GO:0000226 | microtubule cytoskeleton organization |
| Biological Process | GO:0000278 | mitotic cell cycle |
| Biological Process | GO:0006406 | mRNA export from nucleus |
| Biological Process | GO:0006289 | nucleotide-excision repair |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0015031 | protein transport |
| Biological Process | GO:0032465 | regulation of cytokinesis |
| Biological Process | GO:0007283 | spermatogenesis |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.