Search Results
Overview
| Uniprot ID | P42830 |
|---|---|
| Protein Name | C-X-C motif chemokine 5 |
| Gene Name | CXCL5 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 101 | PEAPFLKKVIQKILD |
| 105 | FLKKVIQKILDGGNK |
| 112 | KILDGGNKEN***** |
Function
Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes
Protein Sequence
10
MSLLSSRAAR
20
VPGPSSSLCA
30
LLVLLLLLTQ
40
PGPIASAGPA
50
AAVLRELRCV
60
CLQTTQGVHP
70
KMISNLQVFA
80
IGPQCSKVEV
90
VASLKNGKEI
100
CLDPEAPFLK
110
KVIQKILDGG
NKEN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005615 | extracellular space |
| Molecular Function | GO:0008009 | chemokine activity |
| Molecular Function | GO:0045236 | CXCR chemokine receptor binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Biological Process | GO:0061844 | antimicrobial humoral immune response mediated by antimicrobial peptide |
| Biological Process | GO:0007267 | cell-cell signaling |
| Biological Process | GO:0071222 | cellular response to lipopolysaccharide |
| Biological Process | GO:0006935 | chemotaxis |
| Biological Process | GO:0006954 | inflammatory response |
| Biological Process | GO:0030593 | neutrophil chemotaxis |
| Biological Process | GO:0008284 | positive regulation of cell population proliferation |
| Biological Process | GO:0007165 | signal transduction |
Reference
[1] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.