Search Results
Overview
| Uniprot ID | P43351 |
|---|---|
| Protein Name | DNA repair protein RAD52 homolog |
| Gene Name | RAD52 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 177 | DYLRSLNKLPRQLPL |
Function
Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase
Protein Sequence
10
MSGTEEAILG
20
GRDSHPAAGG
30
GSVLCFGQCQ
40
YTAEEYQAIQ
50
KALRQRLGPE
60
YISSRMAGGG
70
QKVCYIEGHR
80
VINLANEMFG
90
YNGWAHSITQ
100
QNVDFVDLNN
110
GKFYVGVCAF
120
VRVQLKDGSY
130
HEDVGYGVSE
140
GLKSKALSLE
150
KARKEAVTDG
160
LKRALRSFGN
170
ALGNCILDKD
180
YLRSLNKLPR
190
QLPLEVDLTK
200
AKRQDLEPSV
210
EEARYNSCRP
220
NMALGHPQLQ
230
QVTSPSRPSH
240
AVIPADQDCS
250
SRSLSSSAVE
260
SEATHQRKLR
270
QKQLQQQFRE
280
RMEKQQVRVS
290
TPSAEKSEAA
300
PPAPPVTHST
310
PVTVSEPLLE
320
KDFLAGVTQE
330
LIKTLEDNSE
340
KWAVTPDAGD
350
GVVKPSSRAD
360
PAQTSDTLAL
370
NNQMVTQNRT
380
PHSVCHQKPQ
390
AKSGSWDLQT
400
YSADQRTTGN
410
WESHRKSQDM
KKRKYDPS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0032991 | protein-containing complex |
| Cellular Component | GO:0032993 | protein-DNA complex |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0003697 | single-stranded DNA binding |
| Biological Process | GO:0034599 | cellular response to oxidative stress |
| Biological Process | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing |
| Biological Process | GO:0000730 | DNA recombinase assembly |
| Biological Process | GO:0006310 | DNA recombination |
| Biological Process | GO:0006302 | double-strand break repair |
| Biological Process | GO:0000724 | double-strand break repair via homologous recombination |
| Biological Process | GO:0045002 | double-strand break repair via single-strand annealing |
| Biological Process | GO:0006312 | mitotic recombination |
| Biological Process | GO:2000819 | regulation of nucleotide-excision repair |
Reference
[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.