Search Results
Overview
| Uniprot ID | P47971 |
|---|---|
| Protein Name | Neuronal pentraxin-1 |
| Gene Name | Nptx1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 76 | KETILSQKETIRELT |
Function
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses
Protein Sequence
10
MLAGRAARTC
20
ALLALCLLGS
30
RAQDFGPTRF
40
ICTSVPVDAD
50
MCAASVAAGG
60
AEELRSNVLQ
70
LRETVLQQKE
80
TILSQKETIR
90
ELTTKLGRCE
100
SQSTLDAGPG
110
EARSGGGRKQ
120
PGSGKNTMGD
130
LSRTPASETL
140
SQLGQTLQSL
150
KTRLENLEQY
160
SRLNSSSQTN
170
SLKDLLQSKI
180
DDLERQVLSR
190
VNTLEEGKGG
200
PKNDTEERAK
210
IESALTSLHQ
220
RISELEKGQK
230
DNRPGDKFQL
240
TFPLRTNYMY
250
AKVKKSLPEM
260
YAFTVCMWLK
270
SSAAPGVGTP
280
FSYAVPGQAN
290
ELVLIEWGNN
300
PMEILINDKV
310
AKLPFVINDG
320
KWHHICVTWT
330
TRDGVWEAYQ
340
DGTQGGNGEN
350
LAPYHPIKPQ
360
GVLVLGQEQD
370
TLGGGFDATQ
380
AFVGELAHFN
390
IWDRKLTPGE
400
VYNLATCSSK
410
ALSGNVIAWA
420
ESQIEIFGGA
430
TKWTFEACRQ
IN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0043083 | synaptic cleft |
| Cellular Component | GO:0030133 | transport vesicle |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0060385 | axonogenesis involved in innervation |
| Biological Process | GO:0071333 | cellular response to glucose stimulus |
| Biological Process | GO:0035865 | cellular response to potassium ion |
| Biological Process | GO:0043653 | mitochondrial fragmentation involved in apoptotic process |
| Biological Process | GO:0006839 | mitochondrial transport |
| Biological Process | GO:0099645 | neurotransmitter receptor localization to postsynaptic specialization membrane |
| Biological Process | GO:0097107 | postsynaptic density assembly |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.