Search Results
Overview
| Uniprot ID | P48147 |
|---|---|
| Protein Name | Prolyl endopeptidase |
| Gene Name | PREP |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 233 | AEFPDEPKWMGGAEL |
| 414 | IYHCDLTKEELEPRV |
Function
Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long
Protein Sequence
10
MLSLQYPDVY
20
RDETAVQDYH
30
GHKICDPYAW
40
LEDPDSEQTK
50
AFVEAQNKIT
60
VPFLEQCPIR
70
GLYKERMTEL
80
YDYPKYSCHF
90
KKGKRYFYFY
100
NTGLQNQRVL
110
YVQDSLEGEA
120
RVFLDPNILS
130
DDGTVALRGY
140
AFSEDGEYFA
150
YGLSASGSDW
160
VTIKFMKVDG
170
AKELPDVLER
180
VKFSCMAWTH
190
DGKGMFYNSY
200
PQQDGKSDGT
210
ETSTNLHQKL
220
YYHVLGTDQS
230
EDILCAEFPD
240
EPKWMGGAEL
250
SDDGRYVLLS
260
IREGCDPVNR
270
LWYCDLQQES
280
SGIAGILKWV
290
KLIDNFEGEY
300
DYVTNEGTVF
310
TFKTNRQSPN
320
YRVINIDFRD
330
PEESKWKVLV
340
PEHEKDVLEW
350
IACVRSNFLV
360
LCYLHDVKNI
370
LQLHDLTTGA
380
LLKTFPLDVG
390
SIVGYSGQKK
400
DTEIFYQFTS
410
FLSPGIIYHC
420
DLTKEELEPR
430
VFREVTVKGI
440
DASDYQTVQI
450
FYPSKDGTKI
460
PMFIVHKKGI
470
KLDGSHPAFL
480
YGYGGFNISI
490
TPNYSVSRLI
500
FVRHMGGILA
510
VANIRGGGEY
520
GETWHKGGIL
530
ANKQNCFDDF
540
QCAAEYLIKE
550
GYTSPKRLTI
560
NGGSNGGLLV
570
AACANQRPDL
580
FGCVIAQVGV
590
MDMLKFHKYT
600
IGHAWTTDYG
610
CSDSKQHFEW
620
LVKYSPLHNV
630
KLPEADDIQY
640
PSMLLLTADH
650
DDRVVPLHSL
660
KFIATLQYIV
670
GRSRKQSNPL
680
LIHVDTKAGH
690
GAGKPTAKVI
700
EEVSDMFAFI
710
ARCLNVDWIP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0004181 | metallocarboxypeptidase activity |
| Molecular Function | GO:0070012 | oligopeptidase activity |
| Molecular Function | GO:0004252 | serine-type endopeptidase activity |
| Molecular Function | GO:0008236 | serine-type peptidase activity |
| Biological Process | GO:0002003 | angiotensin maturation |
| Biological Process | GO:0006508 | proteolysis |
Reference
PMID: N/A