Search Results
Overview
| Uniprot ID | P48788 |
|---|---|
| Protein Name | Troponin I, fast skeletal muscle |
| Gene Name | TNNI2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 132 | ALLGSKHKVCMDLRA |
Function
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity
Protein Sequence
10
MGDEEKRNRA
20
ITARRQHLKS
30
VMLQIAATEL
40
EKEESRREAE
50
KQNYLAEHCP
60
PLHIPGSMSE
70
VQELCKQLHA
80
KIDAAEEEKY
90
DMEVRVQKTS
100
KELEDMNQKL
110
FDLRGKFKRP
120
PLRRVRMSAD
130
AMLKALLGSK
140
HKVCMDLRAN
150
LKQVKKEDTE
160
KERDLRDVGD
170
WRKNIEEKSG
180
MEGRKKMFES
ES
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005861 | troponin complex |
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0031014 | troponin T binding |
| Biological Process | GO:0060048 | cardiac muscle contraction |
| Biological Process | GO:0045893 | positive regulation of DNA-templated transcription |
| Biological Process | GO:0003009 | skeletal muscle contraction |
Reference
[1] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.