Search Results
Overview
| Uniprot ID | P48819 |
|---|---|
| Protein Name | Vitronectin |
| Gene Name | VTN |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 163 | YCYELDEKAVRPGYP |
| 200 | QGKTYLFKGSQYWRF |
Function
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway (By similarity)
Protein Sequence
10
MAPLRPLLML
20
ALLAWVALAD
30
QESCKGRCTD
40
GFIAERKCQC
50
DELCSYYQSC
60
CTDYVAECKP
70
QVTRGDVFLQ
80
PDDEYRAYDY
90
HEETRHNTSV
100
QEEQRIPVLL
110
AKTEETPVLK
120
PEEEAPPPGP
130
QTDDLGVPEE
140
ELCSGKPFDA
150
FTNLKNGSVF
160
AFRGLYCYEL
170
DEKAVRPGYP
180
KLIQDVWGIK
190
GPIDAAFTRI
200
NCQGKTYLFK
210
GSQYWRFDDG
220
VLDPNYPREI
230
SEGFKGIPDD
240
VDAALALPAH
250
SYSGRERVYF
260
FKGKQYWEYV
270
FQQQPSREEC
280
EGSSPSDVFA
290
HFALMQRDSW
300
EDIFRLLFWS
310
HSFGGAIEPR
320
VISQDWLGLP
330
EQVDAAMAGQ
340
IYISGSALKP
350
SQPKMTKSAR
360
RSGKRYRSRR
370
GRGRGRGHSR
380
SQKSHRQSRS
390
TWLPWFSSEE
400
TGPGGYNYDD
410
YKMDWLVPAT
420
CEPIQSVYFF
430
SGEEYYRVNL
440
RTQRVDTVTP
450
PYPRSIAQYW
LGCPVPDQK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0031012 | extracellular matrix |
| Cellular Component | GO:0005615 | extracellular space |
| Molecular Function | GO:0050840 | extracellular matrix binding |
| Molecular Function | GO:0008201 | heparin binding |
| Molecular Function | GO:0005178 | integrin binding |
| Molecular Function | GO:0030247 | polysaccharide binding |
| Molecular Function | GO:0005044 | scavenger receptor activity |
| Biological Process | GO:0033627 | cell adhesion mediated by integrin |
| Biological Process | GO:0007160 | cell-matrix adhesion |
| Biological Process | GO:0006955 | immune response |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.