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Overview

Uniprot IDP49088
Protein NameAsparagine synthetase [glutamine-hydrolyzing]
Gene NameAsns
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
556 ARTLTHYKSTAKA**

Function

No function data available.

Protein Sequence

10 MCGIWALFGS 20 DDCLSVQCLS 30 AMKIAHRGPD 40 AFRFENVNGY 50 TNCCFGFHRL 60 AVVDPLFGMQ 70 PIRVRKYPYL 80 WLCYNGEIYN 90 HKALQQRFEF 100 EYQTNVDGEI 110 ILHLYDKGGI 120 EKTICMLDGV 130 FAFILLDTAN 140 KKVFLGRDTY 150 GVRPLFKALT 160 EDGFLAVCSE 170 AKGLVSLKHS 180 TTPFLKVEPF 190 LPGHYEVLDL 200 KPNGKVASVE 210 MVKYHHCTDE 220 PLHAIYDSVE 230 KLFPGFEIET 240 VKNNLRILFN 250 NAIKKRLMTD 260 RRIGCLLSGG 270 LDSSLVAASL 280 LKQLKEAQVP 290 YALQTFAIGM 300 EDSPDLLAAR 310 KVANYIGSEH 320 HEVLFNSEEG 330 IQSLDEVIFS 340 LETYDITTVR 350 ASVGMYLISK 360 YIRKNTDSVV 370 IFSGEGSDEL 380 TQGYIYFHKA 390 PSPEKAEEES 400 ERLLKELYLF 410 DVLRADRTTA 420 AHGLELRVPF 430 LDHRFSSYYL 440 SLPPEMRIPK 450 DGIEKHLLRE 460 TFEDSNLLPK 470 EILWRPKEAF 480 SDGITSVKNS 490 WFKILQDFVE 500 HQVDDAMMSE 510 ASQKFPFNTP 520 QTKEGYYYRQ 530 IFEHHYPGRA 540 DWLTHYWMPK 550 WINATDPSAR 560 TLTHYKSTAK A

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Molecular Function GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0042802 identical protein binding
Biological Process GO:0042149 cellular response to glucose starvation
Biological Process GO:0032870 cellular response to hormone stimulus
Biological Process GO:0070981 L-asparagine biosynthetic process
Biological Process GO:0001889 liver development
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0045931 positive regulation of mitotic cell cycle
Biological Process GO:1904044 response to aldosterone
Biological Process GO:0043200 response to amino acid
Biological Process GO:0032354 response to follicle-stimulating hormone
Biological Process GO:0009416 response to light stimulus
Biological Process GO:0009612 response to mechanical stimulus
Biological Process GO:0031667 response to nutrient levels
Biological Process GO:0009636 response to toxic substance

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.