Search Results
Overview
| Uniprot ID | P49418 |
|---|---|
| Protein Name | Amphiphysin |
| Gene Name | AMPH |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 159 | LEALQSSKRKDESRI |
| 27 | AQEKVLQKLGKADET |
| 30 | KVLQKLGKADETKDE |
| 35 | LGKADETKDEQFEEY |
| 47 | EEYVQNFKRQEAEGT |
| 5 | ***MADIKTGIFAKN |
Function
May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton
Protein Sequence
10
MADIKTGIFA
20
KNVQKRLNRA
30
QEKVLQKLGK
40
ADETKDEQFE
50
EYVQNFKRQE
60
AEGTRLQREL
70
RGYLAAIKGM
80
QEASMKLTES
90
LHEVYEPDWY
100
GREDVKMVGE
110
KCDVLWEDFH
120
QKLVDGSLLT
130
LDTYLGQFPD
140
IKNRIAKRSR
150
KLVDYDSARH
160
HLEALQSSKR
170
KDESRISKAE
180
EEFQKAQKVF
190
EEFNVDLQEE
200
LPSLWSRRVG
210
FYVNTFKNVS
220
SLEAKFHKEI
230
AVLCHKLYEV
240
MTKLGDQHAD
250
KAFTIQGAPS
260
DSGPLRIAKT
270
PSPPEEPSPL
280
PSPTASPNHT
290
LAPASPAPAR
300
PRSPSQTRKG
310
PPVPPLPKVT
320
PTKELQQENI
330
ISFFEDNFVP
340
EISVTTPSQN
350
EVPEVKKEET
360
LLDLDFDPFK
370
PEVTPAGSAG
380
VTHSPMSQTL
390
PWDLWTTSTD
400
LVQPASGGSF
410
NGFTQPQDTS
420
LFTMQTDQSM
430
ICNLAESEQA
440
PPTEPKAEEP
450
LAAVTPAVGL
460
DLGMDTRAEE
470
PVEEAVIIPG
480
ADADAAVGTL
490
VSAAEGAPGE
500
EAEAEKATVP
510
AGEGVSLEEA
520
KIGTETTEGA
530
ESAQPEAEEL
540
EATVPQEKVI
550
PSVVIEPASN
560
HEEEGENEIT
570
IGAEPKETTE
580
DAAPPGPTSE
590
TPELATEQKP
600
IQDPQPTPSA
610
PAMGAADQLA
620
SAREASQELP
630
PGFLYKVETL
640
HDFEAANSDE
650
LTLQRGDVVL
660
VVPSDSEADQ
670
DAGWLVGVKE
680
SDWLQYRDLA
690
TYKGLFPENF
TRRLD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015629 | actin cytoskeleton |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0031256 | leading edge membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0008021 | synaptic vesicle |
| Cellular Component | GO:0030672 | synaptic vesicle membrane |
| Molecular Function | GO:0005543 | phospholipid binding |
| Biological Process | GO:0007268 | chemical synaptic transmission |
| Biological Process | GO:0006897 | endocytosis |
| Biological Process | GO:0048488 | synaptic vesicle endocytosis |
Reference
[1] Yang YH, Wang QC, Kong J, Yang JT, Liu JF. Global profiling of lysine lactylation in human lungs.. Proteomics 23(15):e2200437. 2023 Aug. PMID: 37170646.
[2] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.