Search Results
Overview
| Uniprot ID | P50127 |
|---|---|
| Protein Name | N-acetyllactosaminide alpha-1,3-galactosyltransferase |
| Gene Name | GGTA1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 331 | NKYFLLNKPTKILSP |
Function
Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid. Preferentially glycosylates proteins, can synthesize galactose-alpha(1,3)-galactose on glycoproteins but cannot synthesize the glycolipid called isogloboside 3 (iGb3) (By similarity)
Protein Sequence
10
MNVKGRVVLS
20
MLLVSTVMVV
30
FWEYINSPEG
40
SLFWIYQSKN
50
PEVGSSAQRG
60
WWFPSWFNNG
70
THSYHEEEDA
80
IGNEKEQRKE
90
DNRGELPLVD
100
WFNPEKRPEV
110
VTITRWKAPV
120
VWEGTYNRAV
130
LDNYYAKQKI
140
TVGLTVFAVG
150
RYIEHYLEEF
160
LISANTYFMV
170
GHKVIFYIMV
180
DDISRMPLIE
190
LGPLRSFKVF
200
EIKSEKRWQD
210
ISMMRMKTIG
220
EHILAHIQHE
230
VDFLFCMDVD
240
QVFQNNFGVE
250
TLGQSVAQLQ
260
AWWYKAHPDE
270
FTYERRKESA
280
AYIPFGQGDF
290
YYHAAIFGGT
300
PTQVLNITQE
310
CFKGILQDKE
320
NDIEAEWHDE
330
SHLNKYFLLN
340
KPTKILSPEY
350
CWDYHIGMSV
360
DIRIVKIAWQ
370
KKEYNLVRNN
I
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0031985 | Golgi cisterna |
| Cellular Component | GO:0032580 | Golgi cisterna membrane |
| Cellular Component | GO:0031982 | vesicle |
| Molecular Function | GO:0016757 | glycosyltransferase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0047276 | N-acetyllactosaminide 3-alpha-galactosyltransferase activity |
| Biological Process | GO:0005975 | carbohydrate metabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.