Search Results
Overview
| Uniprot ID | P50238 |
|---|---|
| Protein Name | Cysteine-rich protein 1 |
| Gene Name | CRIP1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 22 | ERVTSLGKDWHRPCL |
| 49 | GHAEHEGKPYCNHPC |
| 64 | YAAMFGPKGFGRGGA |
| 77 | GAESHTFK******* |
| 9 | PKCPKCNKEVYFAER |
Function
Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein
Protein Sequence
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0042277 | peptide binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0071236 | cellular response to antibiotic |
| Biological Process | GO:0071493 | cellular response to UV-B |
| Biological Process | GO:0007507 | heart development |
| Biological Process | GO:0006955 | immune response |
| Biological Process | GO:0008630 | intrinsic apoptotic signaling pathway in response to DNA damage |
| Biological Process | GO:0060741 | prostate gland stromal morphogenesis |
| Biological Process | GO:0010468 | regulation of gene expression |
| Biological Process | GO:0010043 | response to zinc ion |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.
[3] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[4] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.