Search Results
Overview
| Uniprot ID | P50411 |
|---|---|
| Protein Name | Protein phosphatase inhibitor 2 |
| Gene Name | Ppp1r2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 103 | TPEILAKKLAAAEGS |
| 113 | AAEGSEPKFRTREQE |
| 12 | TASHRPIKGILKNKT |
| 18 | IKGILKNKTSTTSSV |
Function
Inhibitor of protein-phosphatase 1
Protein Sequence
10
MAASTASHRP
20
IKGILKNKTS
30
TTSSVVASAE
40
QPRRTVEEEL
50
SKKSQKWDEM
60
NILATYHPAD
70
KDYGLMKIDE
80
PDTPYHNMIG
90
DDEDVCSDSE
100
GNEVMTPEIL
110
AKKLAAAEGS
120
EPKFRTREQE
130
SSGEEDNDLS
140
PEEREKKRQF
150
EMKRKLHYNE
160
GLNIKLARQL
170
ISKDLHDDDE
180
DEEMSETADA
190
DSMNIEESNQ
200
GSTAGDHLQH
KSQSS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0043197 | dendritic spine |
| Cellular Component | GO:0030426 | growth cone |
| Molecular Function | GO:0140678 | molecular function inhibitor activity |
| Molecular Function | GO:0019904 | protein domain specific binding |
| Molecular Function | GO:0004864 | protein phosphatase inhibitor activity |
| Biological Process | GO:0005977 | glycogen metabolic process |
| Biological Process | GO:0035556 | intracellular signal transduction |
| Biological Process | GO:0009966 | regulation of signal transduction |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.