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Overview

Uniprot IDP50878
Protein NameLarge ribosomal subunit protein uL4
Gene NameRpl4
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
274 WRKAASLKSNYNLPM
364 AAAALAAKSEKIVPE
377 PEKGAGDKKPAVGKK

Function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Protein Sequence

10 MACARPLISV 20 YSEKGESSGK 30 NVTLPAVFKA 40 PIRPDIVNFV 50 HTNLRKNNRQ 60 PYAVSELAGH 70 QTSAESWGTG 80 RAVARIPRVR 90 GGGTHRSGQG 100 AFGNMCRGGR 110 MFAPTKTWRR 120 WHRRVNTTQK 130 RYAICSALAA 140 SALPALVMSK 150 GHCVEEVPEL 160 PLVVEDKVES 170 YKKTKEAVQL 180 LKKLKAWNDI 190 KKVYASQRMR 200 AGKGKMRNRR 210 RIQRRGPCII 220 YNEDNGIIKA 230 FRNIPGITLL 240 NVSKLNILKL 250 APGGHVGRFC 260 IWTESAFRKL 270 DELYGTWRKA 280 ASLKSNYNLP 290 MHKMMNTDLS 300 RILKSPEIQR 310 ALRAPRKKIH 320 RRVLKKNPLK 330 NLRIMLKLNP 340 YAKTMRRNTI 350 LRQARNHKLR 360 VKKLEAAAAA 370 LAAKSEKIVP 380 EKGAGDKKPA 390 VGKKGKKPVD 400 AKKLKKPAGK 410 KVVTKKPAEK 420 KPTTEEKKSA A

Gene Ontology

Classification GO ID Description
Cellular Component GO:0031672 A band
Cellular Component GO:0005634 nucleus
Cellular Component GO:0014069 postsynaptic density
Cellular Component GO:1990904 ribonucleoprotein complex
Cellular Component GO:0005791 rough endoplasmic reticulum
Molecular Function GO:0008097 5S rRNA binding
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0003360 brainstem development
Biological Process GO:0030154 cell differentiation
Biological Process GO:0002181 cytoplasmic translation
Biological Process GO:0045773 positive regulation of axon extension
Biological Process GO:0050772 positive regulation of axonogenesis
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0022625 cytosolic large ribosomal subunit
Cellular Component GO:0022626 cytosolic ribosome
Cellular Component GO:0015934 large ribosomal subunit

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.