Search Results
Overview
| Uniprot ID | P51175 |
|---|---|
| Protein Name | Protoporphyrinogen oxidase |
| Gene Name | Ppox |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 37 | VILVEGSKRLGGWIR |
Function
Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Protein Sequence
10
MGRTVIVLGG
20
GISGLAASYH
30
LIRGPSPPKV
40
ILVEGSKRLG
50
GWIRSIRGSD
60
GAIFELGPRG
70
IRPAGALGAR
80
TLLLVSELGL
90
ESEVLPVRGD
100
HPAAQNRFLY
110
VGGTLHPLPS
120
GLRGLLRPSP
130
PFSKPLFWAG
140
LRELLKPRGK
150
EPDETVHSFA
160
QRRLGPEVAS
170
LAMDSLCRGV
180
FAGNSRELSI
190
RSCFPSLFQA
200
EQTHRSILLG
210
LLLGAGQSPQ
220
PDSSLIRQAR
230
AERWSQWSLR
240
GGLEVLPQAL
250
HNHLASKGVT
260
VLSGQPVCGL
270
SLQPEGRWKV
280
SLGDSSLEAD
290
HIISAIPASE
300
LSKLLPAEAA
310
PLARILSTIK
320
AVSVAVVNLQ
330
YRGACLPVQG
340
FGHLVPSSED
350
PTVLGIVYDS
360
VAFPEQDGNP
370
PSLRVTVMLG
380
GYWLQKLKAA
390
GHQLSPELFQ
400
QQAQEAAATQ
410
LGLKEPPSHC
420
LVHLHKNCIP
430
QYTIGHWQKL
440
DSAMQFLTAQ
450
RLPLTLAGAS
460
YEGVAVNDCI
470
ESGRQAAVAV
LGTESNS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005758 | mitochondrial intermembrane space |
| Cellular Component | GO:0031966 | mitochondrial membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0004729 | oxygen-dependent protoporphyrinogen oxidase activity |
| Biological Process | GO:0006784 | heme A biosynthetic process |
| Biological Process | GO:0006785 | heme B biosynthetic process |
| Biological Process | GO:0006783 | heme biosynthetic process |
| Biological Process | GO:0006779 | porphyrin-containing compound biosynthetic process |
| Biological Process | GO:0006782 | protoporphyrinogen IX biosynthetic process |
| Biological Process | GO:0046501 | protoporphyrinogen IX metabolic process |
| Biological Process | GO:0009410 | response to xenobiotic stimulus |
Reference
[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.