Search Results
Overview
| Uniprot ID | P51884 |
|---|---|
| Protein Name | Lumican |
| Gene Name | LUM |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 148 | DLQLTHNKITKLGSF |
| 172 | HLQHNRLKEDAVSAA |
| 181 | DAVSAAFKGLKSLEY |
| 184 | SAAFKGLKSLEYLDL |
| 226 | NIPDEYFKRFNALQY |
| 292 | QLEKFDIKSFCKILG |
| 305 | LGPLSYSKIKHLRLD |
| 59 | YCDELKLKSVPMVPP |
Function
No function data available.
Protein Sequence
10
MSLSAFTLFL
20
ALIGGTSGQY
30
YDYDFPLSIY
40
GQSSPNCAPE
50
CNCPESYPSA
60
MYCDELKLKS
70
VPMVPPGIKY
80
LYLRNNQIDH
90
IDEKAFENVT
100
DLQWLILDHN
110
LLENSKIKGR
120
VFSKLKQLKK
130
LHINHNNLTE
140
SVGPLPKSLE
150
DLQLTHNKIT
160
KLGSFEGLVN
170
LTFIHLQHNR
180
LKEDAVSAAF
190
KGLKSLEYLD
200
LSFNQIARLP
210
SGLPVSLLTL
220
YLDNNKISNI
230
PDEYFKRFNA
240
LQYLRLSHNE
250
LADSGIPGNS
260
FNVSSLVELD
270
LSYNKLKNIP
280
TVNENLENYY
290
LEVNQLEKFD
300
IKSFCKILGP
310
LSYSKIKHLR
320
LDGNRISETS
330
LPPDMYECLR
VANEVTLN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0031012 | extracellular matrix |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0005583 | fibrillar collagen trimer |
| Cellular Component | GO:0140150 | gel phase of interstitial matrix |
| Cellular Component | GO:0005796 | Golgi lumen |
| Cellular Component | GO:0043202 | lysosomal lumen |
| Molecular Function | GO:0005518 | collagen binding |
| Molecular Function | GO:0005201 | extracellular matrix structural constituent |
| Molecular Function | GO:0030021 | extracellular matrix structural constituent conferring compression resistance |
| Biological Process | GO:0051216 | cartilage development |
| Biological Process | GO:0030199 | collagen fibril organization |
| Biological Process | GO:0032914 | positive regulation of transforming growth factor beta1 production |
| Biological Process | GO:1904010 | response to Aroclor 1254 |
| Biological Process | GO:0070848 | response to growth factor |
| Biological Process | GO:0007601 | visual perception |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.
[3] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.