Search Results

Overview

Uniprot IDP52481
Protein NameAdenylyl cyclase-associated protein 2
Gene NameCap2
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
176 NRVLRDYKHSDLRHV
289 TDDKKIYKNPSLRAQ
330 PVLELEGKKWRVEYQ
369 STLQIKGKVNSITVD

Function

Involved in the regulation of actin polymerization

Protein Sequence

10 MADMLGLMQR 20 LEFAVSRLER 30 LSSGLHEPPG 40 GCGEVNSLSR 50 GIVAPSVEAF 60 DKLINSMVAE 70 FLKNSRVLAG 80 DVETHAEMVH 90 GAFQAQRAFL 100 LMVSQHQQPQ 110 ENEVAVLLKP 120 ISEKIQEIQT 130 FRERNRGSDM 140 FNHLSAVSES 150 IAALGWIAVS 160 PKPGPYVKEM 170 NDAATFYTNR 180 VLRDYKHSDL 190 RHVDWVRSYL 200 KIWSELQAYI 210 KEHHTTGLTW 220 SKTGPVASTA 230 SAFSILSSGP 240 GLPPPPPPPP 250 PPGPPPPFEN 260 EGGKEEPSPS 270 RSALFAQLNQ 280 GEAITKGLRH 290 VTDDKKIYKN 300 PSLRAQGQIR 310 SPTKTRTPSP 320 TSSKSNSPQK 330 HAPVLELEGK 340 KWRVEYQEDR 350 NDLVISETEL 360 KQVAYIFKCD 370 KSTLQIKGKV 380 NSITVDNCKK 390 FGLVFDHVVG 400 IVEVINSKDI 410 QIQVMGRVPT 420 ISINKTEGCH 430 LYLSKDALDC 440 EIVSAKSSEM 450 NVLVPQGDDY 460 REFPIPEQFK 470 TIWDGSKLIT EPAEIMA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0005886 plasma membrane
Cellular Component GO:0098794 postsynapse
Cellular Component GO:0014069 postsynaptic density
Molecular Function GO:0003779 actin binding
Molecular Function GO:0008179 adenylate cyclase binding
Molecular Function GO:0042802 identical protein binding
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0007015 actin filament organization
Biological Process GO:0000902 cell morphogenesis
Biological Process GO:0007010 cytoskeleton organization
Biological Process GO:0099140 presynaptic actin cytoskeleton organization
Biological Process GO:1905274 regulation of modification of postsynaptic actin cytoskeleton

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.