Search Results
Overview
| Uniprot ID | P52555 |
|---|---|
| Protein Name | Endoplasmic reticulum resident protein 29 |
| Gene Name | Erp29 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 231 | ISKLIENKMSEGKKE |
Function
Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER
Protein Sequence
10
MAAAVPGAVS
20
LSPLLSVLLG
30
LLLLSAPHGA
40
SGLHTKGALP
50
LDTVTFYKVI
60
PKSKFVLVKF
70
DTQYPYGEKQ
80
DEFKRLAENS
90
ASSDDLLVAE
100
VGISDYGDKL
110
NMELSEKYKL
120
DKESYPVFYL
130
FRDGDFENPV
140
PYSGAVKVGA
150
IQRWLKGQGV
160
YLGMPGCLPA
170
YDALAGQFIE
180
ASSREARQAI
190
LKQGQDGLSG
200
VKETDKKWAS
210
QYLKIMGKIL
220
DQGEDFPASE
230
LARISKLIEN
240
KMSEGKKEEL
250
QRSLNILTAF
260
RKKGAEKEEL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0009986 | cell surface |
| Biological Process | GO:1902235 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway |
| Biological Process | GO:0034976 | response to endoplasmic reticulum stress |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005788 | endoplasmic reticulum lumen |
| Cellular Component | GO:0042470 | melanosome |
| Cellular Component | GO:0005790 | smooth endoplasmic reticulum |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0051087 | protein-folding chaperone binding |
| Biological Process | GO:0006886 | intracellular protein transport |
| Biological Process | GO:0010629 | negative regulation of gene expression |
| Biological Process | GO:0050709 | negative regulation of protein secretion |
| Biological Process | GO:0010628 | positive regulation of gene expression |
| Biological Process | GO:0043410 | positive regulation of MAPK cascade |
| Biological Process | GO:0006457 | protein folding |
| Biological Process | GO:0009306 | protein secretion |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.