Search Results
Overview
| Uniprot ID | P54227 |
|---|---|
| Protein Name | Stathmin |
| Gene Name | Stmn1 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 9 | ASSDIQVKELEKRAS |
Function
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis (By similarity). Involved in the control of the learned and innate fear
Protein Sequence
10
MASSDIQVKE
20
LEKRASGQAF
30
ELILSPRSKE
40
SVPDFPLSPP
50
KKKDLSLEEI
60
QKKLEAAEER
70
RKSHEAEVLK
80
QLAEKREHEK
90
EVLQKAIEEN
100
NNFSKMAEEK
110
LTHKMEANKE
120
NREAQMAAKL
130
ERLREKDKHV
140
EEVRKNKESK
DPADETEAD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Biological Process | GO:0031115 | negative regulation of microtubule polymerization |
| Biological Process | GO:0035024 | negative regulation of Rho protein signal transduction |
| Biological Process | GO:0051497 | negative regulation of stress fiber assembly |
| Biological Process | GO:0070495 | negative regulation of thrombin-activated receptor signaling pathway |
| Biological Process | GO:0031175 | neuron projection development |
| Biological Process | GO:0030334 | regulation of cell migration |
| Biological Process | GO:0031110 | regulation of microtubule polymerization or depolymerization |
| Biological Process | GO:0009615 | response to virus |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0043005 | neuron projection |
| Molecular Function | GO:0015631 | tubulin binding |
| Biological Process | GO:0007409 | axonogenesis |
| Biological Process | GO:0061436 | establishment of skin barrier |
| Biological Process | GO:0048012 | hepatocyte growth factor receptor signaling pathway |
| Biological Process | GO:0007019 | microtubule depolymerization |
| Biological Process | GO:0000281 | mitotic cytokinesis |
| Biological Process | GO:0007052 | mitotic spindle organization |
Reference
[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.