Search Results
Overview
| Uniprot ID | P54613 |
|---|---|
| Protein Name | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform |
| Gene Name | PPP2R1B |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 146 | AHFVPLVKRLASGDW |
| 176 | PRASNAVKAEIRQHF |
Function
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit
Protein Sequence
10
NSAGAAAPGT
20
GPVAAGGDGD
30
DSLYPIAVLI
40
DELRNEDVQL
50
RLNSIKKLST
60
IALALGVERT
70
RTELLPFLTD
80
TIYDEDEVLL
90
ALAEQLGNFT
100
GLVGGPDFAH
110
CLLPPLESLA
120
TVEETVVRDK
130
AVESLRQISQ
140
EHTPVALEAH
150
FVPLVKRLAS
160
GDWFTSRTSA
170
CGLFSVCYPR
180
ASNAVKAEIR
190
QHFRSLCSDD
200
TPMVRRAAAS
210
KLGEFAKVLE
220
LDSVKSEIVP
230
LFTNLASDEQ
240
DSVRLLAVEA
250
CVSIAQLLSQ
260
DDLEALVMPT
270
LRQAAEDKSW
280
RVRYMVADKF
290
SELQRAVGPK
300
ITLNDLIPAF
310
QNLLKDCEAE
320
VRAAAAHKVK
330
ELCENLPIEG
340
RETIIMNQIL
350
PCIKELVSDT
360
NQHVKSALAS
370
VIMGLSTILG
380
KENTIEHLLP
390
LFLAQLKDEC
400
PEVRLNIISN
410
LDCVNEVIGI
420
RQLSQSLLPA
430
IVELAEDAKW
440
RVRLAIIEYM
450
PLLAGQLGVE
460
FFDEKLNSLC
470
MAWLVDHVYA
480
IREAATNNLM
490
KLVQKFGTEW
500
AQNTIVPKVL
510
VMANDPNYLH
520
RMTTLFCINV
530
LSEACGQEIT
540
TKQMLPIVLK
550
MAGDQVANVR
560
FNVAKSLQKI
570
GPILDTDALQ
580
EEVKPVLQKL
590
GQDEDMDVKY
600
FAQEAISVLA
LA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0000159 | protein phosphatase type 2A complex |
| Molecular Function | GO:0019888 | protein phosphatase regulator activity |
| Biological Process | GO:0051754 | meiotic sister chromatid cohesion, centromeric |
| Biological Process | GO:0051225 | spindle assembly |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.