Search Results
Overview
| Uniprot ID | P54690 |
|---|---|
| Protein Name | Branched-chain-amino-acid aminotransferase, cytosolic |
| Gene Name | Bcat1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 240 | PKFVRSWKGGTGDFK |
Function
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine
Protein Sequence
10
MAYLSRATAT
20
LARQDCSNGC
30
SASYAEEEEL
40
EASTESYDEE
50
GGSEASTQTF
60
RAKDLIITKA
70
DVLKKKPDPS
80
SLVFGASFTD
90
HMLMVEWTSK
100
YGWDKPHIKP
110
FENLSIHPAA
120
SVLHYAVELF
130
EGLKAFRGVD
140
NKIRLFRPDL
150
NMKRMCRSAV
160
RTTLPEFDKE
170
ELLQCVLQLI
180
QLDREWVPYS
190
TSASLYIRPT
200
FIGIEPSLGV
210
KKPSKALLFV
220
ILSPVGSYFS
230
NGTFSPVSLW
240
ANPKFVRSWK
250
GGTGDFKMGC
260
NYGSSLLAQC
270
EAAENGCHQV
280
LWLYGKENRI
290
TEVGTMNLFL
300
YWINKDGEEE
310
LATPPLDGVI
320
LPGVTRQSIL
330
ELGEEWGEFK
340
VCERHITMDD
350
LSTALEENRV
360
KEMFGSGTAC
370
VVCPVASILY
380
KGQMLHIPTM
390
ENGHKLSSRI
400
MAKLTDIQYG
410
RIKSEWTLEL
P
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0004084 | branched-chain-amino-acid transaminase activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0052656 | L-isoleucine-2-oxoglutarate transaminase activity |
| Molecular Function | GO:0052654 | L-leucine-2-oxoglutarate transaminase activity |
| Molecular Function | GO:0052655 | L-valine-2-oxoglutarate transaminase activity |
| Biological Process | GO:0009083 | branched-chain amino acid catabolic process |
| Biological Process | GO:0009098 | L-leucine biosynthetic process |
| Biological Process | GO:0009099 | L-valine biosynthetic process |
| Biological Process | GO:0006629 | lipid metabolic process |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.