Search Results
Overview
| Uniprot ID | P54709 |
|---|---|
| Protein Name | Sodium/potassium-transporting ATPase subunit beta-3 |
| Gene Name | ATP1B3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 194 | PRIDCVSKNEDIPNV |
Function
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known
Protein Sequence
10
MTKNEKKSLN
20
QSLAEWKLFI
30
YNPTTGEFLG
40
RTAKSWGLIL
50
LFYLVFYGFL
60
AALFSFTMWV
70
MLQTLNDEVP
80
KYRDQIPSPG
90
LMVFPKPVTA
100
LEYTFSRSDP
110
TSYAGYIEDL
120
KKFLKPYTLE
130
EQKNLTVCPD
140
GALFEQKGPV
150
YVACQFPISL
160
LQACSGMNDP
170
DFGYSQGNPC
180
ILVKMNRIIG
190
LKPEGVPRID
200
CVSKNEDIPN
210
VAVYPHNGMI
220
DLKYFPYYGK
230
KLHVGYLQPL
240
VAVQVSFAPN
250
NTGKEVTVEC
260
KIDGSANLKS
270
QDDRDKFLGR
VMFKITARA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016324 | apical plasma membrane |
| Cellular Component | GO:0016323 | basolateral plasma membrane |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0042470 | melanosome |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0005890 | sodium:potassium-exchanging ATPase complex |
| Cellular Component | GO:0036126 | sperm flagellum |
| Molecular Function | GO:0001671 | ATPase activator activity |
| Molecular Function | GO:0051117 | ATPase binding |
| Molecular Function | GO:0030674 | protein-macromolecule adaptor activity |
| Molecular Function | GO:0141109 | transporter activator activity |
| Biological Process | GO:0030007 | intracellular potassium ion homeostasis |
| Biological Process | GO:0006883 | intracellular sodium ion homeostasis |
| Biological Process | GO:0086009 | membrane repolarization |
| Biological Process | GO:1903288 | positive regulation of potassium ion import across plasma membrane |
| Biological Process | GO:1903278 | positive regulation of sodium ion export across plasma membrane |
| Biological Process | GO:1990573 | potassium ion import across plasma membrane |
| Biological Process | GO:0071805 | potassium ion transmembrane transport |
| Biological Process | GO:0072659 | protein localization to plasma membrane |
| Biological Process | GO:0050821 | protein stabilization |
| Biological Process | GO:0036376 | sodium ion export across plasma membrane |
| Biological Process | GO:0035725 | sodium ion transmembrane transport |
Reference
PMID: N/A