Search Results

Overview

Uniprot IDP54920
Protein NameAlpha-soluble NSF attachment protein
Gene NameNAPA
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
203 PLLKYSAKDYFFKAA

Function

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane (PubMed:15980433)

Protein Sequence

10 MDNSGKEAEA 20 MALLAEAERK 30 VKNSQSFFSG 40 LFGGSSKIEE 50 ACEIYARAAN 60 MFKMAKNWSA 70 AGNAFCQAAQ 80 LHLQLQSKHD 90 AATCFVDAGN 100 AFKKADPQEA 110 INCLMRAIEI 120 YTDMGRFTIA 130 AKHHISIAEI 140 YETELVDIEK 150 AIAHYEQSAD 160 YYKGEESNSS 170 ANKCLLKVAG 180 YAALLEQYQK 190 AIDIYEQVGT 200 NAMDSPLLKY 210 SAKDYFFKAA 220 LCHFCIDMLN 230 AKLAVQKYEE 240 LFPAFSDSRE 250 CKLMKKLLEA 260 HEEQNVDSYT 270 ESVKEYDSIS 280 RLDQWLTTML 290 LRIKKTIQGD EEDLR

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0030425 dendrite
Cellular Component GO:0070062 extracellular exosome
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0042599 lamellar body
Cellular Component GO:0016020 membrane
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0031594 neuromuscular junction
Cellular Component GO:0043204 perikaryon
Cellular Component GO:0045211 postsynaptic membrane
Cellular Component GO:0048787 presynaptic active zone membrane
Cellular Component GO:0008021 synaptic vesicle
Cellular Component GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex
Cellular Component GO:0043195 terminal bouton
Molecular Function GO:0044877 protein-containing complex binding
Molecular Function GO:0000149 SNARE binding
Molecular Function GO:0005483 soluble NSF attachment protein activity
Molecular Function GO:0019905 syntaxin binding
Biological Process GO:0006891 intra-Golgi vesicle-mediated transport
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0061025 membrane fusion
Biological Process GO:0010807 regulation of synaptic vesicle priming
Biological Process GO:0055093 response to hyperoxia
Biological Process GO:0035494 SNARE complex disassembly
Biological Process GO:0035249 synaptic transmission, glutamatergic
Biological Process GO:0016082 synaptic vesicle priming

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.